China Adapalene 106685-40-9 Good Quality Skin Care Pharmaceutical Chemicals, Find details about China Adapalene, 106685-40-9 from Adapalene 106685-40-9 Good Quality Skin Care Pharmaceutical Chemicals
| Identification | By IR | Complies |
| Solubility | Practically insoluble in water and ethanol(96%),sparingly soluble in tetrahydrofuran. | Complies |
| Appearance of Solution | The solution is clear and not more intensely coloured than reference solution BY6 | Complies |
| Loss on Drying | ≤ 0.50% | 0.16% |
| Heavy Metals | ≤ 20ppm | Complies |
| Sulfated Ash | ≤ 0.10% | 0.07% |
| Residual Solvents | Tetrahydrofuran: ≤720ppm | 630ppm |
| Acetic acid ≤5000ppm | ND | |
| Methanol ≤3000ppm | ND | |
| Dichloromethane ≤600ppm | ND | |
| N,N-dimethyl formamide ≤880ppm | ND | |
| Related Substances | Impurity A: ≤0.30% | 0.21% |
| Impurity D: ≤0.20% | 0.13% | |
| Impurity C: ≤0.15% | ND | |
| Other unknown impurity: ≤0.10% | 0.06% | |
| Total Impurities: ≤0.50% | 0.45% | |
| Assay (HPLC basis on drying) | 98.0%~102.0% | 99.60% |
| Reference Standard | EP8.0 Standard | |
| Conclusion | The product complied to EP8.0 standard. | |
| Storage | Preserve in tight,light-resistant containers in a cool place | |