China API Wholesale Bp/USP Gemfibrozil for Hyperlipidemia and Cholesterol, Find details about China 25812-30-0, Pharma Grade from API Wholesale Bp/USP Gemfibrozil for Hyperlipidemia and Cholesterol
Gemfibrozil is a hyperlipidemic agent that elevates plasma HDL and lowers triglycerides and LDL by stabilizing apoA-I mRNA transcripts.
It was found to inhibit inducible nitric oxide synthase by inhibiting the activation of nuclear factor-kappaB, activator protein-1 and CCAAT/enhancer-binding protein β.
Items | Standards | Results | |
Appearance | White or off-white solid powder | Complies | |
Identification | By IR | Complies | |
By HPLC | Complies | ||
Solubility | Soluble in DMF, sparingly soluble in THF, slightly soluble in methanol and acetonitrile, very sightly soluble in ethanol and dichloromethane, insoluble in water. | Complies | |
Polymorphic Form | Polymorphic form 1 | Complies | |
Melting Point | 211ºC~216ºC | 212.6ºC~214.5ºC | |
Water Content | ≤ 0.50% | 0.12% | |
Heavy Metals | ≤ 20ppm | Complies | |
Residue on Ignition | ≤ 0.20% | 0.08% | |
Related Substance | Any single impurity: ≤0.10% | 0.05% | |
Total Impurities: ≤1.00% | 0.18% | ||
Assay (on the anhydrous basis) | 98.0%~102.0% | 99.88% | |
Particle Size | D90: ≤100µm | Complies |
1. Reduce triglyceride levels.
2. Reduce very low density lipoprotein (VLDL) levels.
3. Modest reduction of low density lipoprotein (LDL) levels.
4. Moderate increase in high density lipoprotein (HDL) levels.
Packaging: 25kg drum.
Shipping: Within 7 days of order confirmation.