Herbal Cinchona Extract Quinine 99% Powder CAS 130-95-0 Quinine 

Product Name	Quinine Powder
CAS No	60-93-5
Appearance	White powder
Specification	99%
Certificate	ISO,SGS,HALAL,KOSHER

Quinine HCL powder is a medication used to prevent and treat malaria and to treat babesiosis. This includes to treat malaria due to Plasmodium falciparum that is resistant to chloroquine when artesunate is not available.While used for restless legs syndrome it is not recommended for this purpose. It can be taken by mouth or used intravenously. Malaria that is resistant to quinine occur in certain areas of the world.

 

 

Items	Specification	Test result
Description	A white or almost white powder	Complies
Solubility	Very soluble in water; soluble in ethanol (99%)	Complies
Melting point	233-235 ºC	234ºC
Specific optical rotation	-223-229° (C=2, 0.1M HCl)	-241º
SULPHATED ASH	≤0.1%	0.05%
Barium	This product is 0.2g, dissolved in 10ml water, add dilute sulfuric acid 1ml, 15 minutes, turbidity shall not occur	Complies
The related impurities	≤ 1.5%	0.90%
Loss on drying	6.0%-10.0%	8.00%
Residue on ignition	≤ 0.15%	0.05%
PH	pH=2.0-3.0	2.5
Assay	99.0%-101.0%	99.20%
Conclusion	The results conforms with Specifications

 

An alkaloid derived from the bark of the cinchona tree. It is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona that have been used for that purpose since before 1633.

Quinine is also a mild antipyretic and analgesic and has been used in common cold preparations for that purpose. It was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis.

Quinine is also useful in some muscular disorders, especially nocturnal leg cramps and myotonia congenita, because of its direct effects on muscle membrane and sodium channels. The mechanisms of its antimalarial effects are not well understood.