Tacrolimus, a macrolide isolated from streptomycete, has strong immunosuppressant activity that specifically binds and inhibits calmodulin phosphatase activity and il-2 signaling transcription, thereby inhibiting T cell activation and inhibiting
ChemicalbookTNF-, IL-1 and IL-6 production and T-cell-dependent B cell proliferation.Tacrolimus inhibited T-cell activation more strongly and had fewer adverse reactions than cyclosporin, another calmodulin phosphatase inhibitor.

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Shaanxi Jeujon Bio-Tech LTD is located in Xi'an City, Shannxi Province, China. Now it is the leading researcher and one of the biggest manufacturer in both Pharmaceutials and high technology chemicals area. Jeujon is specialized in Research, Production, Process and Sales. We have absolute advantage because of strong research strength, modern management system and high-quality marketing team.There are 20 experts in our research team. We insist in innovation and produce high quality products. And we have GMP standard workshop and complete stainless extraction equipment. The superior product quality is guaranteed by 300,000 level air-conditioning clear system within purification, drying and packing procedures. We have 2 sales departments over 30 people and sell our products all over the world.We also have strong professional research and development team, talented personnel and completely equipped laboratory for the quality controlling. Various Detection Device is equipped in Jeujon, such as HPLC, GC, Spectrophotometer, AAS, Polarimeter, Auto titrators, BOD Incubators, COD Incubators, melting point apparatus and so on.
Our products are mainly sold to pharmacy company and health care company in both China and abroad, like Europe, USA, Japan and so on.For customer's needs, OEM service is also supplied. If you have a good plan in new product production but lack of laboratory device and human resource, we are glad to sovle this problem for you.Our company's business is based on Honest, Trustworthy,Constantly to Go Beyond and Achieve Mutual Win. Sincerely hope to strengthen exchanges and cooperation with friends from both home and abroad.