Pharmaceutical Raw Powder CAS 20537-88-6 Amifostine
DescriptionAmifostine, an organic thiophosphate, was introduced for the reduction of cisplatin-induced renal toxicity in patients with advanced ovarian cancer. It is also a radio-protective agent. Amifostine is a prodrug which is rapidly dephosphorylated, preferentially in non-tumor tissues to the active thiol. This agent binds to chemotherapeutic drugs and free radicals released by radiotherapy. The protective effect of amifostine was observed in a wide range of normal organs including bone marrow and gastrointestinal mucosa without interfering with the anti-tumor effect of chemohadiotherapy, indicating an increased therapeutic index for existing cancer treatment. Amifostine is also being evaluated as a cytoprotective in other types of tumors including lung, breast, head and neck cancers. It was reported to be a potent mucolytic with potential in cystic fibrosis.
Certificate of Analysis
Item | Specification | Test Results |
Appearance | White crystalline powder | Conform |
Taste | Tasteless | Conform |
Odor | Odorless | Conform |
Clarity and colour of solution | Clear and colourless | Conform |
Creatine Monohydrate Assay | ≥99.5% | 0.9996 |
Loss on Drying | ≤12.00% | 0.1134 |
Residue on Ignition | ≤0.1% | Conform |
Sulphate | ≤0.1% | Conform |
Heavy metals | ≤10ppm | Conform |
Lead | ≤3ppm | Conform |
Cadmium | ≤1ppm | Conform |
Arsenic | ≤1ppm | Conform |
Mercury | ≤0.1ppm | Conform |
Dicyanamide | ≤20ppm | Conform |
Cyanide | ≤1ppm | Conform |
Creatinine | ≤100ppm | 52 |
Bulk density | ≥430g/L | 468 |
Tapped bulk density | ≥550g/L | 720 |
Residual Organic Solvents | Neg. | Neg. |
Total plate count | ≤1000CFU/G | Conform |
Yeasts & Moulds | ≤1000CFU/G | Conform |
E-coli | NOT PRESENT | Negative |
Staphylococcus Aureus in | NOT PRESENT | Negative |
Salmonella in 1 G | NOT PRESENT | Negative |
Coliforms | NOT PRESENT | Negative |
Conclusion : The result conforms the USP32 . |
Related Products
Product Name | CAS NO. | Specification |
Praziquantel | 55268-74-1 | 99% |
Niclosamide | 50-65-7 | 99% |
Lufenuron | 103055-07-8 | 99% |
Ivermectin | 70288-86-7 | 99% |
Eprinomectin | 123997-26-2 | 99% |
Doramectin | 117704-25-3 | 99% |
Avermectin | 71751-41-2 | 99% |
Albendazole | 54965-21-8 | 99% |
Levamisole Hydrochloride | 16595-80-5 | 99% |
Fenpropathrin | 39515-41-8 | 99% |
Bifenazate | 149877-41-8 | 99% |
Chlorfluazuron | 71422-67-8 | 99% |
Tetramisole Hydrochloride | 5086-74-8 | 99% |
Fenbendazole | 43210-67-9 | 99% |
Mebendazole | 31431-39-7 | 99% |
Febantel | 58306-30-2 | 99% |
Oxyclozanide | 2277-92-1 | 99% |
Moxidectin | 113507-06-5 | 99% |
Amprolium Hydrochloride | 137-88-2 | 99% |
Toltrazuril | 69004-03-1 | 99% |
pyrimethamine | 58-14-0 | 99% |
Packing & ShippingCompany Infomation
Xi'an Wucine Bio Industries Inc is a national key high-tech enterprise,which mainly specializes in the R&D,operation and production of pharmaceuticals,and intermediates.Our company is situated in E&T development zone,xi'an city shaanxi,it is easy of access.Our company has independent R&D center,raw material synthesis workshop,has advanced quality instruments and equipmentm,several product patents there are 15 experts in our research team.We insist in innovation and produce high quality products.FAQ1.Are you a manufacturer or trade company?
We are a professional manufacturer.
2.What's your payment terms?
Standard terms: T/T in advance and Western Union.
Also L/C at sight is acceptable for large amount. 3.What's your shipping time?
We have a large stock, which means we can deliver the goods to you immediately.
4.How do you ensure the quality of your products?
Strict QC with 6 steps testing from raw material purchase to finished product.
5.How do you ship the order normally?
For large qty order,ship the goods by sea.
For small qty order, by air or express. We supply optional express for you, including DHL,FEDEX,UPS,TXT,EMS,and so on.
6.What's your loading port?
Usually Shanghai, Qingdao, Tianjin, Guangzhou