Clotrimazole is a synthetic pyrrole antifungal drug, which has inhibitory effect on a variety of pathogenic fungi. It can also have a bactericidal effect when the concentration is high. Clotrimazole inhibits the biosynthesis of fungal ergosterol and other sterols by interfering with the activity of cytochrome P450; damages the fungal cell membrane and changes its permeability, causing the loss of important substances in the cell; it can also inhibit fungal triglycerides and phospholipids The biosynthesis; this product can still inhibit the activity of oxidation and peroxidase, causing excessive accumulation of peroxide in the cell, causing degeneration and necrosis of the fungal subcellular structure. Clotrimazole has a broad-spectrum antifungal activity. It has a good antibacterial effect against Epidermophyton, Trichophyton, Aspergillus, Pigmenting fungus, Cryptococcus and Candida, and has good antibacterial effect against Sporothrix schenckii and dermatitis blastomycetes. , Coccidioides spp., Histoplasma spp., etc. also have certain antibacterial activity.
 
  Clotrimazole has a good antibacterial effect against Candida, Cryptococcus, Aspergillus, Algae, Dermatophytes, etc. in vivo and in vitro. The effect on superficial skin mycoses is similar to griseofulvin, and it is similar to griseofulvin. The curative effect of mycosis is similar to that of amphotericin B. It has a good effect on visceral pathogenic fungi such as Candida albicans, Cryptococcus neoformans, coccidioides and histoplasma, etc. It has a better effect on Candida albicans than nystatin. Strong. Fungi are not easy to develop resistance to this product. This product is easy to be absorbed orally, and can be taken orally to treat systemic and deep fungal infections, such as aspergillosis, candidiasis, cryptococcosis, coccidioidomycosis, histoplasmosis (dogs, cats) and fungal sepsis Wait. For severe deep fungal infections, it should be combined with amphotericin B. External use can also treat superficial fungal infections, such as cockscomb ringworm, tinea corporis and tinea corporis of livestock. Not effective on tinea capitis. Clotrimazole is also effective against certain Gram-positive bacteria and Trichomonas vaginalis.

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 Hebei Lianghong Biotechnology Co., Ltd. It was founded in 2021, located in Shijiazhuang, Hebei Province, which is specialized in the research of production and trade of pharmaceutical intermediate and cosmetic raw materials.Our products have spread over more than 50 countries in the world, Most of the products produced and sold are exported abroad,and it is well-received in all around the word for its excellent quality.At the same time in case to maintain good relations of cooperation with domestic manufactures, we actively develop new products,new customers and constantly meet the needs of customers at home and abroad. We sincerely welcome more clients to cooperate with us.