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Pharmaceuticals Chemical Cyclopamine 4449-51-8 with Safe Delivery

China Pharmaceuticals Chemical Cyclopamine 4449-51-8 with Safe Delivery, Find details about China Cyclopamine, Raw Powder Cyclopamine from Pharmaceuticals Chemical Cyclopamine 4449-51-8 with Safe Delivery

Model NO.
Cyclopamine
CAS Number
4449-51-8
Product Name
Cyclopamine
Shelf Life
2 Years
Usage
Intermediate
Delivery Time
7-10 Days
Trademark
biolang
Transport Package
Bottle and Drum
Specification
1kg/bottle or 25kgs/drum
Origin
China
HS Code
2300890000
Model NO.
Cyclopamine
CAS Number
4449-51-8
Product Name
Cyclopamine
Shelf Life
2 Years
Usage
Intermediate
Delivery Time
7-10 Days
Trademark
biolang
Transport Package
Bottle and Drum
Specification
1kg/bottle or 25kgs/drum
Origin
China
HS Code
2300890000
Pharmaceuticals Chemical Cyclopamine 4449-51-8 with Safe Delivery
Pharmaceuticals Chemical  Cyclopamine 4449-51-8 with Safe Delivery

Product Description
Cyclopamine (11-deoxojervine)
Cyclopamine (11-deoxojervine) CAS 4449-51-8
Chinese Name         Huangbaan
Botanical Resource:      Veratrum californicum or Veratrum nigrum L
CAS No.:              4449-51-8
Molecular formula:     C27H41NO2
Molecular weight:       411.62
Melting point:      237-238ºC
Specific optical Rotation:[α]20ºCD  -44.2º
Product Specification    98% Cyclopamine (11-deoxojervine)
Product Introduction
Cyclopamine (11-deoxojervine) is a naturally-occurring chemical that belongs to the group of steroidal jerveratrum alkaloids. It is a teratogen isolated from the corn lily (Veratrum californicum) that causes usually fatal birth defects. It can prevent the fetal brain from dividing into two lobes (holoprosencephaly) and cause the development of a single eye (cyclopia). It does so by suppressing the hedgehog gene (Hh). Cyclopamine is useful in studying the role of Hh in normal development, and as a potential treatment for certain cancers in which Hh is overexpressed.
Physical Properties:      
White Powder; Odorless; Melting point:237-238ºC; Solubility:5mg·ml-1 Methanl;10mg·ml-1DMF.
Loss on drying:  ≤0.5% 

Physiological Functions & Applications
Cyclopamine inhibits the hedgehog signaling pathway (Hh) by influencing the balance between the active and inactive forms of the Smoothened protein.Cyclopamine is currently being investigated as a treatment agent in basal cell carcinoma, medulloblastoma, and rhabdomyosarcoma, tumors that result from excessive Hh activity [2], glioblastoma, and as a treatment agent for multiple myeloma.
HPLC-ELSD Chromatogram of 98% Cyclopamine
Cyclopamine (11-deoxojervine) CAS 4449-51-8

LC-MS of cyclopamine
  Cyclopamine (11-deoxojervine) CAS 4449-51-8
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Packing and delivery 

S (-) -3-Hydroxy-Gamma-Butyrolacton-E CAS 7331-52-4

S (-) -3-Hydroxy-Gamma-Butyrolacton-E CAS 7331-52-4

Company information
Pharmaceuticals Chemical Cyclopamine 4449-51-8 with Safe Delivery
Our advantages

1.For products exported we can offer COA Certificate and official PI.

2.We are manufacturer with own lab and factory, can provide high quality products with factory price. 

3.Products can be sent out in 24 hours after payment. Tracking number available, fixed service person are 7x24h for you to contact.

4.Secure and discreet shipment. Various transportation methods for your choice, like DHL/UPS/TNT/FedEx/SF-express.

5.Customs pass and satisfied rate ≥99%.

6.For hot sale products we have stock in there for transferring. 

7.Products purity is test by our quality department strictly before sending, and you can

askthe third testing organization come and inspect, such as (SGS/ CTI/ ITS), only after our confirmation will we send it out to you.

8.We have different couriers to different countries.

9.We have clients throughout the world.
FAQ

Q1: Can i get some samples? 
A: Yes, we can supply the free sample, but the shipping cost be paid by our customers.

Q2: How to start orders or make payments? 
A: Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T, Western Union or Paypal or Escrow(Alibaba).

Q3: How to confirm the Product Quality before placing orders? 
A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

Q4:What's your MOQ? 
A:Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Q5: How about delivery lead time? 
A:Delivery lead time: About 3-5 days after payment confirmed. (Chinese holiday not included)



 

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