Factory Supply High Purity Ambroxol hydrochloride CAS 23828-92-4 with best price

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Product Description:

    Ambroxol Hydrochloride is an active metabolite of the expectorant bromexin (N-demethylated, cyclohexyl counterpoint introduced trans-hydroxyl), which is less toxic than bromexin and more active than bromexin.

    Hydro-chloric acid ammonium bromide cable is by the German boehringer ingelheim developed mucus of solute, the drug in the early 1980 s in Germany first, then in France, Italy, Japan, Spain and many other countries have been listed, the solute is a new generation of phlegm, can improve the row of phlegm, and can promote lung surface active substance and airway secretions, and the function of cilia movement. In clinical practice, it can regulate mucus and mucus secretion, activate ciliary vibration, easily dilute sputum, strengthen mucus outward transport, easy to discharge, it can also promote the synthesis of pulmonary surface active substances, to maintain alveolar tension, ensure the Chemicalbook lung function indicators; Promote the penetration of antibiotics to tissues to improve the concentration and enhance the bactericidal effect; Antioxidant, reduce the release of inflammatory mediators, to reduce inflammation; In conjunction with bronchial spasmolytic substances, to improve the efficacy of antispasmolytic drugs. The drug in clinic, therefore, can be widely used in with acute or chronic respiratory diseases of respiratory tract abnormal secretion, especially the expectorant treatment of chronic bronchitis, aid in the treatment of neonatal respiratory distress syndrome and lung surgery, has low toxicity, curative effect, and can with good synergistic effect of antibiotics and wait for an advantage, as one of the most commonly used expectorant.

1. cough and phlegm effect
    Ambroxol hydrochloride mainly acts on the secreting cells of the respiratory tract, regulating the secretion of mucous and serous substances, increasing the secretion of serous substances, cracking the polysaccharide fibers of acidic glycoprotein in the sputum, inhibiting the synthesis of acidic protein in mucous glands and goblet Chemicalbook cells, reducing the viscosity of sputum, making the sputum thin and easy to discharge. At the same time, the drug can also increase the frequency and intensity of respiratory ciliary movement, promote sputum discharge and respiratory self-purification.

2. Antioxidation
    Ambroxol hydrochloride has a significant antioxidant effect and plays an important role in the reactivity of free oxygen groups in pulmonary diseases. Some studies have shown that ambroxol has a strong inhibitory effect on the H2O2 chemicalbook produced by neutrophils. In addition, ambroxol also activates the cellular glutathione system and promotes the synthesis of intracellular glutathione (GSH), thus counteracting the damaging effects of oxygen free radicals.

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