China CAS 1454846-35-5 Lorlatinib PF-06463922 with Laboratory Customization High Purity, Find details about China 1454846-35-5, Lorlatinib from CAS 1454846-35-5 Lorlatinib PF-06463922 with Laboratory Customization High Purity
Product Name | lorlatinib |
Synonyms | UNII:OSP71S83EU (R)-2<sup>6</sup>-amino-5<sup>5</sup>-fluoro-1<sup>1</sup>,4,7-trimethyl-6-oxo-1<sup>1</sup>H-3-oxa-7-aza-2(3,5)-pyridina-1(4,3)-pyrazola-5(1,2)-benzenacyclooctaphane-1<sup>5</sup>-carbonitrile 2H-8,4-Methenopyrazolo[4,3-h][2,5,11]benzoxadiazacyclotetradecine-3-carbonitrile, 7-amino-12-fluoro-10,15,16,17-tetrahydro-2,10,16-trimethyl-15-oxo-, (10R)- (16R)-19-Amino-13-fluoro-4,8,16-trimethyl-9-oxo-17-oxa-4,5,8,20-tetraazatetracyclo[16.3.1.0.0]docosa-1(22),2,5,10,12,14,18,20-octaene-3-carbonitrile lorlatinib (10R)-7-amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2H-4,8- methenopyrazolo[4,3-h][2,5,11]benzoxadiazacyclotetradecine-3-carbonitrile PF06463922 PF-06463922 |
CAS NO | 1454846-35-5 |
ENIENCS | N/A |
Molecular Formula | C21H19FN6O2 |
Molecular Weight | 406.413 |
Melting point | N/A |
Boiling Point | 675.0±55.0 °C at 760 mmHg |
Flash Point | 362.1±31.5 °C |
Density | 1.4±0.1 g/cm3 |
Assay | 99% |
Grade | Pharmaceutical Grade |
Solubility | N/A |
Appearance | white powder |
Storage | Keep the reservoir sealed Store in a tight container in a cool, dry place |
Packaging and Shipping | Aluminum foil bag, cartons, plastic contain,drums or as required; By Express, by Air, by Sea according to the Amount. |
Usage | Lorlatinib is a potent, dual ALK/ROS1 inhibitor that inhibits ROS1, wild ALK, and mutant ALK (L1196M) at 0.02 nM, 0.07 nM, and 0.7 nM, respectively. |
1-10kgs: packaging Aluminum Foil Bag inside and carton box outside
25kgs: packaging Fiber drum outside and plastic bag inside
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