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Methyl Calcium L-5-Methyltetrahydrofolate (L-5-MTHF- Ca )

China Methyl Calcium L-5-Methyltetrahydrofolate (L-5-MTHF-Ca), Find details about China White Powder, CAS 151533-22-1 from Methyl Calcium L-5-Methyltetrahydrofolate (L-5-MTHF-Ca)

Model NO.
AWI
Nutrient Composition
Amino Acid
Trademark
AWI
Transport Package
1kg Bags/25kg Carton or as Client′s Demand
Origin
China
Model NO.
AWI
Nutrient Composition
Amino Acid
Trademark
AWI
Transport Package
1kg Bags/25kg Carton or as Client′s Demand
Origin
China
Methyl Calcium L-5-Methyltetrahydrofolate (L-5-MTHF-Ca)
Product NameCalcium L-5-Methyltetrahydrofolate
Batch Number20190802Quantity5kgs
Quality StandardUSPPacking0.5 kg/tin
Manufacture Date2019.07.25Expiry Date2021.07.24


Application and Uses 

L-5-MTHF-Ca (5-mthf) is a naturally occurring salt-forming methyl derivative of folic acid. 5-mthf is also known as levomethyl-folate, which is the most biologically active and functional of folic acid. Form, more easily absorbed than ordinary folic acid. Common folic acid must be converted to type 1 methyl folate to participate in two major metabolic pathways: methylation and DNA synthesis, the only form of free folate normally present in human plasma and cells is 5-mthf. Lack of folic acid is usually caused by vitamin deficiency, which is insufficient for absorption. During pregnancy and breastfeeding, the need for folic acid is increased during the growth of children.
 
Application:
1. Mainly for folic acid antagonists (such as methotrexate, pyrimethamine, benzyl cefalexin and trimethoprim) antidote, it's usually used for prevention of methotrexate dose or overdose treatment caused severe toxic effects.

2. Folic acid treatment of the following diseases, such as inflammatory diarrhea and protein-energy malnutrition (poor nutrition), pregnancy or infancy megaloblastic anemia caused by poor.

3. as adjuvant therapy for colon cancer, rectal cancer

4. Combined with 5-FU and treatment of digestive tract tumors or other 5-FU-sensitive tumors. High-dose CF used in conjunction with 5-FU (LF), the basic programme is currently the treatment of colon and rectal cancer.

5. For children with leukemia, lymphoma, and osteosarcoma, such as high dose MTX treatment when rescued.
 
Methyl Calcium L-5-Methyltetrahydrofolate (L-5-MTHF-Ca)
 
Methyl Calcium L-5-Methyltetrahydrofolate (L-5-MTHF-Ca)
ItemStandardTest Result
AppearanceWhite to light yellow crystalline powderConforms
Specific rotation                 (on anhydrous substance)[α]25D(C=1.5% in water)+40.6°
IdentificationHNMRHNMR should be identical with that of referenceConforms
 HPLCThe retention time of the major peak in the chromatogram of Assay preparation corresponds to that in the chromatogram of the standard preparation,as obtained in the AssayConforms
Calcium content
(on anhydrous substance)		7.0%~8.5%7.7%
D-5-Methylfolate≤1.0%Undetected
(HPLC) Related compoundsDimethyltetrahydrofolic acid≤0.15%0.07%
 Single Impurity≤1.0%0.23%
 Total Impurity≤2.5%0.94%
Residual solventEthanolNMT 5000ppmUndetected
Water≤16.0%14.7%
Chloride(CI)≤0.5%Conforms
Arsenic(As)≤1ppm<1ppm
Boron≤20ppmConforms
Heavy MetalsNMT 20ppm
Pb NMT 1ppm
Cd NMT 0.5ppm
As NMT 1.5ppm
Hg NMT 1.5 ppm		Conforms
Total Plate Count≤100cfu/gConforms
Yeast & Mold≤100cfu/gNo detected
SalmonellaNegativeNo detected
E.ColiNegativeNo detected
Purity>97.5%99.1%
ConclusionThis batch of product complies to the standard.
 Methyl Calcium L-5-Methyltetrahydrofolate (L-5-MTHF-Ca)

AWI Service

1. Supply high quality products with a reasonable price.
2. Keep shipment in time, provide complete customers clearance documents as customs request. 
3. Provide agile and safe payments.
4. We will responsible for all quality issue.
5. Share marketing informations with customers update price in time.
 

FAQ

1. What's your payment terms?
T/T, D/P, L/C, O/A
2. What's your delivery time?
Usually we will arrange the shipment within 14 days.
3. How about the packing? 
Usually with 25 kg bag/carton/drum. 
4. How about the validity of the products? 
Usually 2 or 3 years. 
5. What documents you provide? 
Usually, Commerical Invoice, Packing List, Country of Origin, Insurance Policy, Bill of loading, COA , Health certificate. 
6. What is loading port?
Usually, Qingdao, Tianjin and Shanghai  
Methyl Calcium L-5-Methyltetrahydrofolate (L-5-MTHF-Ca)
Amy Xu 

High-Tech Industry Development Zone,Hefei,China
Welcome meet us at:
Fi Africa 15-17 March 2020 at Cairo Egypt. AWI Booth # H1.D46.
Fi Vietnam 1-3 July 2020 at HCMC Vietnam. AWI Booth # A1.112.

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