cas 154992-24-2 ru58841 powder 
 
RU58841 is an androgen receptor blocker. It binds to androgen receptors with great specificity and tenacity, but does not activate the receptor. Its presence on the receptor prevents androgens such as DHT from binding to and activating the receptor. It has been extensively studied as a topical agent to treat acne and androgenetic alopecia (1, 2, 3).

Androgenetic alopecia, or male-pattern balding, is caused by DHT binding to androgen receptors in the hair follicles. Over time, in susceptible individuals, the activation of the androgen receptors causes the hair follicles to stop producing normal hair and to undergo a process called miniaturization. In laboratory studies, RU58841 has been shown to be quite effective in competing against DHT for access to the androgen receptors.