Lincomycin Hydrochloride Injection is a sterile solution which contains lincomycin hydrochloride which is the monohydrated salt of lincomycin, a substance produced by the growth of a member of the lincolnensis group of Streptomyces lincolnensis (Fam. Streptomycetaceae). The chemical name for lincomycin hydrochloride is Methyl 6,8-dideoxy-6-(1-methyl-trans-4-propyl-L-2-pyrolidinecarboxamido)-1-thio-D-erythro-α-D-galacto-octopyranoside monohydrochloride monohydrate. 

Indiction: 
Lincomycin Hydrochloride Injection is indicated in the treatment of serious infections due to susceptible strains of streptococci, pneumococci, and staphylococci.

Dosage and method of administration:
The drug is administered i.m. and i.v. Daily parenteral dose in adults is 1.8 g, single dose is 0.6 g. In severe infections daily dose may be increased to 2.4 g. The drug is introduced 3 time a day with an interval 8 h. In children the dose is 10-20 mg/kg of body weigh every 8-12 h.

i.v. injection of lincomycin hydrochloride is introduced by drops at the rate of 60-80 drops per min. before injection dilute 2 ml of 30% antibiotic solution (0.6 g) in 250 ml of isotonic solution of sodium chloride.

The course of treatment is 7-14 days, in osteomyelitis 3 weeks and more.

In patients with hepatic and renal failure lincomycin is administered parenterally in daily dose NMT 1.8 g with an interval 12 h.

Storage Situation: Stored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.

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