Veliparib, also known as ABT-888, is a potent and selective Poly (ADP-Ribose) Polymerase (PARP) Inhibitor. Veliparib enhances apoptosis and autophagy in response to treatments that cause DNA breaks, including radiation and DNA alkylation. ABT-888 is an orally bioavailable inhibitor of PARP1 and PARP2.

ABT-888 effectively inhibits PARP, with Ki values of 5.2 and 2.9 nM when acting on PARP-1 and PARP-2, respectively. ABT-888 reduces the survival rate of cloned genes in lung cancer H460 cells and inhibits DNA repair. The combination of ABT-888 and radiation reduces the formation of tumor blood vessels. ABT-888 delays the growth of tumor Chemicalbook of NCI-H460 xenograft model. ABT-888 inhibits PARP in B16F10 and 9L xenograft tumor models, thereby enhancing the anticancer activity of temozolomide.

SOFTGEL

 

Model: 500mg 1000mg 2000mg...

Softgels have a gelatin shell, surrounding a gel or liquid interior.Suitable for all kinds of animal and plant essential oils.

SOFTGEL

 

Model: 500mg 1000mg 2000mg...

Softgels have a gelatin shell, surrounding a gel or liquid interior.Suitable for all kinds of animal and plant essential oils.

SMALL BAG PACKAGE

 

Type:10g, 50g, 100g, 500g, 1000g, 2000g...

Small bag is also a good choice for a samll amount of contents packaged.Customized size,color and label design are available.

SMALL BAG PACKAGE

 

Type:10g, 50g, 100g, 500g, 1000g, 2000g...

Small bag is also a good choice for a samll amount of contents packaged.Customized size,color and label design are available.

BOTTLE

 

Type: PET, PE(HDPE),....

Volume:60cc,120cc, 150cc, 200cc, 250cc...
Customized size,color and label design are available.