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CAS No 638-23-3 S-Carboxymethyl-L-Cysteine, Carbocistein

China CAS No 638-23-3 S-Carboxymethyl-L-Cysteine, Carbocistein, Find details about China S-Carboxymethyl-L-Cysteine, Carbocistein from CAS No 638-23-3 S-Carboxymethyl-L-Cysteine, Carbocistein

Model NO.
S-Carboxymethyl-L-cysteine
CAS
638-23-3
Mf
C5h9no4s
MW
221.252
Density
1.451g/cm3
Boiling Point
393.5 C at 760 Mmhg
Melting Point
208-213 °c (DEC.)
Flash Point
191.8 C
Usage
Animal Pharmaceuticals
Trademark
HNB
Transport Package
1kg/Bag, 25kg/Drum
Specification
Carbocistein
Origin
China
Model NO.
S-Carboxymethyl-L-cysteine
CAS
638-23-3
Mf
C5h9no4s
MW
221.252
Density
1.451g/cm3
Boiling Point
393.5 C at 760 Mmhg
Melting Point
208-213 °c (DEC.)
Flash Point
191.8 C
Usage
Animal Pharmaceuticals
Trademark
HNB
Transport Package
1kg/Bag, 25kg/Drum
Specification
Carbocistein
Origin
China
CAS No 638-23-3 S-Carboxymethyl-L-Cysteine, Carbocistein
Product Name S-carboxymethyl-L-cysteine
CAS number 638-23-3
Molecular formula C5H9NO4S
Molecular weight 179.19
Appearance white to slightly off-white amorphous powder
Melting point205-207ºC
Flash point191.8ºC
Relative density1.451g/cm3

Carbocisteine (INN), also called carbocysteine (USAN), is a mucolytic that reduces the viscosity of sputum and so can be used to help relieve the symptoms of chronic obstructive pulmonary disorder (COPD) and bronchiectasis by allowing the sufferer to bring up sputum more easily. Carbocisteine should not be used with antitussives (cough suppressants) or medicines that dry up bronchial secretions.
Carbocisteine is produced by alkylation of cysteine with chloroacetic acid.

It is an important pharmaceutical raw material; used in the synthesis of a variety of drugs, can reduce the stickiness of respiratory secretions, for the treatment of chronic tracheitis, emphysema, tuberculosis and so on.

CAS No 638-23-3 S-Carboxymethyl-L-Cysteine, Carbocistein

CAS No 638-23-3 S-Carboxymethyl-L-Cysteine, Carbocistein
 

Test Item

Specification

Description

A white or almost white, crystalline powder, particularly insoluble in water and in alcohol. It dissolves in dilute mineral acids and in dilute solutions of alkali hydroxxides.

Identification

A. It complies with the test for specific optical rotation

 

B.  The IR spectrum of the sample is concordant with the spectrum of the reference standard, Carbocisteine CRS

 

C. The principal spot in the chromatogram obtained with the test solution(b) is similar in position,color and size to the principal spot in the chromatogram  obtained with the reference solution(a)

 

D.  Dark red color is produced, which changes to brown and then to yellow within  a few minutes

pH

 2.8~3.0

Specific optical rotation[α]D20

-32.5° to -35.5°(on dried basis)

State of solution (Transmittance)

Solution S is clear and colourless Not less than  96.0%

Nihydrin-positive substances

Not more than 0.5%

Chloride(Cl)

Not more than 0.15%

Sulfate(SO4)

Not more than 0.030%

Heavy metals(Pb)

Not more than 0.001%

Loss on Drying

Not more than 0.5%

Sulfated ash

Not more than 0.30%

Assay

98.5% ~ 101.0%



CAS No 638-23-3 S-Carboxymethyl-L-Cysteine, CarbocisteinCAS No 638-23-3 S-Carboxymethyl-L-Cysteine, CarbocisteinCAS No 638-23-3 S-Carboxymethyl-L-Cysteine, CarbocisteinCAS No 638-23-3 S-Carboxymethyl-L-Cysteine, CarbocisteinCAS No 638-23-3 S-Carboxymethyl-L-Cysteine, CarbocisteinCAS No 638-23-3 S-Carboxymethyl-L-Cysteine, CarbocisteinCAS No 638-23-3 S-Carboxymethyl-L-Cysteine, Carbocistein
CAS No 638-23-3 S-Carboxymethyl-L-Cysteine, Carbocistein
 

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