High Quality Raw Powder Nicergoline Dilasenil Cergodum for Dilatational Resistance Vessel CAS 27848-84-6 with Safe Delivery
China High Quality Raw Powder Nicergoline Dilasenil Cergodum for Dilatational Resistance Vessel CAS 27848-84-6 with Safe Delivery, Find details about China Nicergoline, CAS 27848-84-6 from High Quality Raw Powder Nicergoline Dilasenil Cergodum for Dilatational Resistance Vessel CAS 27848-84-6 with Safe Delivery
Basic Info.
Model NO.
Raw Powder Nicergoline
Appearance
White to Almost White Powder
CAS Number
27848-84-6
Mf
C24h26brn3o3
MW
484.39
Einecs No.
248-694-6
Melting Point
136-138 Celsuis
Boiling Point
544.4-644.0 Celsuis (Predicted)
Storage at
Refrigerator
Shelf Life
2 Years
Delivery Time
7-10 Days
Trademark
Biolang
Transport Package
Foil Bag/Drum
Specification
1kg/bag
Origin
China
HS Code
2323232356
Model NO.
Raw Powder Nicergoline
Appearance
White to Almost White Powder
CAS Number
27848-84-6
Mf
C24h26brn3o3
MW
484.39
Einecs No.
248-694-6
Melting Point
136-138 Celsuis
Boiling Point
544.4-644.0 Celsuis (Predicted)
Storage at
Refrigerator
Shelf Life
2 Years
Delivery Time
7-10 Days
Trademark
Biolang
Transport Package
Foil Bag/Drum
Specification
1kg/bag
Origin
China
HS Code
2323232356
Product Desciption
High Quality Raw Powder Nicergoline Dilasenil Cergodum for Dilatational Resistance Vessel CAS 27848-84-6 with Safe Delivery
| Product Name | Nicergoline |
| CAS NO. | 27848-84-6 |
| MOQ | 1 kg |
| Other Name | Nicergoline |
| Molecular Formular | C24H26BrN3O3 |
| Molecular Weight | 484.385 |
| Appearance | White powder |
| Brand | Monad |
| Purity | 99% |
| Melting Point | 136-138° |
| Density | 1.5±0.1 g/cm3 |
| Boiling Point | 594.4±50.0 °C at 760 mmHg |
| Flash Point | 313.3±30.1 °C |
Description
Nicergoline is a semi-synthetic ergotine derivative with alpha receptor blocking and vascularization effects.
Can strengthen the metabolism of brain cell energy, increase the utilization of oxygen and glucose, promote the conversion of neurotransmitter dopamine and enhance nerve conduction, strengthen the biosynthesis of brain protein, improve brain function.
The drug was absorbed quickly after oral administration, and the absolute bioavailability was less than 5%. The pharmacokinetics of the drug was not affected by age. About 80% of this product is excreted by kidneys. In patients with severe renal insufficiency, the excretion of metabolites in urine is significantly reduced.
Function of Nicergoline
1. Applicable to acute and chronic cerebral vessels
2. Applicable to peripheral circulation disorders
3. Poor brain metabolism and headaches
4. For chronic brain insufficiency syndrome
5. Used for mobility problems
6. Auxiliary treatment of language disorder syndrome, etc.
2. Applicable to peripheral circulation disorders
3. Poor brain metabolism and headaches
4. For chronic brain insufficiency syndrome
5. Used for mobility problems
6. Auxiliary treatment of language disorder syndrome, etc.
Application of Nicergoline
1. Nicergoline is a semi-synthetic ergotine derivative with alpha receptor blocking and vascularization effects.
2. It can enhance the metabolism of brain cell energy, increase the utilization of oxygen and glucose, promote the conversion of neurotransmitter dopamine and enhance nerve conduction, strengthen the biosynthesis of brain protein, and improve brain function.
3. Rapid absorption after oral administration, with absolute bioavailability less than 5%.
4. The pharmacokinetics of the product was not affected by age. About 80% of this product is excreted by kidneys.
5. In patients with severe renal insufficiency, the excretion of metabolites in urine is significantly reduced.
2. It can enhance the metabolism of brain cell energy, increase the utilization of oxygen and glucose, promote the conversion of neurotransmitter dopamine and enhance nerve conduction, strengthen the biosynthesis of brain protein, and improve brain function.
3. Rapid absorption after oral administration, with absolute bioavailability less than 5%.
4. The pharmacokinetics of the product was not affected by age. About 80% of this product is excreted by kidneys.
5. In patients with severe renal insufficiency, the excretion of metabolites in urine is significantly reduced.
COA:
ITEMS | SPECIFICATION | RESULTS | |
Appearance | White or buff powder | White powder | |
Melting point | 133ºC--136ºC | 135--136ºC | |
Specific optical rotation | Conforms | Conform | |
Clarity and color of the solution | Clear | Clear | |
Related substances | Total impurity ≤1.5% | 0.18% | |
Nor-nocergoline (B)≤0.50% | 0.02% | ||
Chioronicergoline (A)≤0.5% | 0.04% | ||
MeLUOL (C)≤0.30% | 0.02% | ||
Unidentified impurity:≤0.30% | 0.06% | ||
Water | ≤0.5% | 0.06% | |
Heavy metal | ≤20ppm | Conform | |
Residue on ignition | ≤0.05% | 0.02% | |
Assay | 98.5%--102% | 99.3% | |
Residue solvents | Conform | Conform | |
1 | Acetone | ≤1000ppm | 450ppm |
2 | Diethyl ether | ≤2000ppm | 140ppm |
3 | Ethanol | ≤1000ppm | 40ppm |
4 | Methanol | ≤1000ppm | 90ppm |
5 | Toluene | ≤500ppm | 30ppm |
6 | Dichloromethan | ≤100ppm | <50ppm |
7 | Triethylamine | ≤500ppm | 230ppm |
Conclusion | Conform with EP 5.0 | ||
Storage :In the shade of dark and situation. And low temperature(+2--+8ºC) | |||
Payment terms: TT,Bitcoin,Western union , Money gram or Bank transfer
Delivery: 1-3 working days after payment confirmed
Shipping: Door to door safe deliver by air,by sea,express including EMS,DHL,UPS,TNT,FedEX
Packaging Details: Safe package or as required
Discount: Large quantity ordered
Prompt shipment after the receipt of your order confirmation.
25kg/drum or 1kg/aluminum foil bag or as customer's requirement
Transit could be DHL,UPS,TNT,EMS,Fedex,and so on.
Usually it take 3-15 days to arrive.
For mass orders, it will be delivered by air or sea.
Our Company:
Shanghai Biolang Bio-logical Co.,LTD is a research and development, production, sales in one high-tech company.Mainly involves API, pharmaceutical intermediates and natural extract etc.
Our philosophy: strengthen cooperation, promote exchanges, interact and win-win!
Our aim: people-oriented, integrity first, quality mainly!
Sincerely looking forward to establish long-term and mutually beneficial business relationship with you!
Why Choose Us?
1.OEM/ODM Available.
2. Raw materials from chinese origin
3. Best quality in your requirement
4. Competitive price in china market
5 Fast delivery and free sample for your evaluation.Stock availability
6.Door to door shipping service is available.
7. Professional documents for your custom clearance.
8. Full experience of large numberscontainers loading in chinese sea port
9. Packing with pallet or as buyer's special request
10. Best after-service after shipment
The more discount you'll get if your order is potential.
Q1 what's the moq?
A: Usually our MOQ is 1kg.But it is based on the different product. Some are 10g.
Q2:Which kind of payment terms do you accept?
A: Payment by T/T, Western Union,Bitcoin or Bank transfer.
Q3.Which transportation do we use?
A:Samples could be DHL, UPS, TNT, EMS, Fedex, and so on. For mass orders, it will be delivered by air or sea.
Q4:How about your delivery time?
Generally, it will take 3 to 5 days after receiving your advance payment.
Q5:How do you treat quality complaint?
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
Q6. How can we trust you?
A: You are always warm welcomed to visit us at any time.Before we start B2B, MIC has audited our company on-spot and approved our credit.
Q7.Do you test all your goods before delivery?
A:Yes, we have 100% test before delivery,International Authorized Third-Party Test for the products if you need are highly welcomed.
Any questions,please feel free to contact us!
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