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Wholesale API Antineoplastic Powder CAS 170729-80-3 Aprepitant in Bulk

China Wholesale API Antineoplastic Powder CAS 170729-80-3 Aprepitant in Bulk, Find details about China CAS 41100-52-1, Aprepitant from Wholesale API Antineoplastic Powder CAS 170729-80-3 Aprepitant in Bulk

Model NO.
ws-Aprepitant
Product Name
Aprepitant
CAS
170729-80-3
Mf
C23h21f7n4o3
Appearance
off-White Crystalline Powder
MOQ
10g
Shelf Life
2 Years
Assay
HPLC 99%
Sample
Available
Nw
534.42700
Einecs
/
Trademark
wison
Transport Package
Silver Foil Bag/Drum
Origin
Shanxi
Model NO.
ws-Aprepitant
Product Name
Aprepitant
CAS
170729-80-3
Mf
C23h21f7n4o3
Appearance
off-White Crystalline Powder
MOQ
10g
Shelf Life
2 Years
Assay
HPLC 99%
Sample
Available
Nw
534.42700
Einecs
/
Trademark
wison
Transport Package
Silver Foil Bag/Drum
Origin
Shanxi

Wholesale API Antineoplastic Powder CAS 170729-80-3 Aprepitant in Bulk

Product Description 
Product nameAprepitant
CAS170729-80-3
purity99%min
MFC23H21F7N4O3
Molecular Weight534.4266624
ColorWhite powder


Aprepitant is an antiemetic chemical compound that belongs to a class of drugs called substance P antagonists. Aprepitant, an antiemetic, is a substance P/neurokinin 1 (NK1) receptor antagonist which, in combination with other antiemetic agents, is indicated for the prevention of acute and delayed nausea and vomiting associated with initial and repeat courses of highly emetogenic cancer chemotherapy. Aprepitant is a selective high-affinity antagonist of human substance P/neurokinin 1 (NK1) receptors. Aprepitant has little or no affinity for serotonin (5-HT3), dopamine, and corticosteroid receptors, the targets of existing therapies for chemotherapy-induced nausea and vomiting (CI NV).

COA

ItemsStandardsResults
AppearanceWhite or off-white crystalline powderWhite solid powder
IdentificationBy IRComplies
By HPLCComplies
SolubilityFreely soluble in dimethyl sulfoxide, insoluble in waterComplies
Specific Rotation+66.0°~ +71.0°+67.0°
Water Content≤ 0.50%0.13%
Loss on Drying≤ 0.50%0.10%
Residue on Ignition≤ 0.10%0.06%
Organic ImpuritiesImpurity AP0: ≤0.15%ND
Impurity AP1: ≤0.15%ND
Impurity AP2: ≤0.15%ND
Desfluoro aprepitant: ≤0.15%ND
Any other individual impurity: ≤0.10%0.06%
Total Impurities: ≤0.30%0.25%
Limit of S,R,S-Enantiomer≤0.10%Complies
Assay98.0%~102.0%99.85%
Residual Solvents
 		Dimethyl sulphoxide: ≤5000ppm650ppm
Methyl tert-butyl ether: ≤5000ppmND
O-xylene: ≤2170ppmND
N,N-isopropyl ethyl amine: ≤50ppm10ppm
Methanol:≤3000ppmND
Methyl isobutyl ketone: ≤5000ppmND
Acetone: ≤5000ppmND
Tetrahydrofuran: ≤720ppmND
Toluene: ≤890ppmND
N-heptane: ≤5000ppmND
Polymorph RXRDThe Diffractogram should exhibit the 2-theta for form-1 at 15.3±0.2º. The Diffractogram should not exhibit the 2-theta peaks fore form-2 at 21.1±0.2ºComplies
Reference StandardUSP 39 Standard
ConclusionThe product complied to USP 39 standard.
StoragePreserve in tight,light-resistant containers in a cool place

Wholesale API Antineoplastic Powder CAS 170729-80-3 Aprepitant in Bulk


 

Wholesale API Antineoplastic Powder CAS 170729-80-3 Aprepitant in Bulk
Wholesale API Antineoplastic Powder CAS 170729-80-3 Aprepitant in Bulk

 FAQ

· Q:What is the MOQ?
· A:1kg. But usually, we accept less quantity such as 100g on the condition that sample charge is 100% paid.


· Q:Can I get a free sample?
· A:Sure! We can supply the free sample, but the shipping cost is paid by our customers.

· Q:Can I get a lower price if I order large quantities?
· A:Yes, cheaper prices with more bigger size orders.

· Q:How to confirm the Product Quality before placing orders?
· A:You can get free samples. you only need to pay the shipping cost or arrange a courier to us and take the samples. Tell me your products specifications and requests, we will manufacture according to your requests.

· Q:How about delivery lead time?
· A:Delivery lead time: About 3-5days after payment confirmed(Chinese holiday not included)

· Q:How to start orders or make payments?
· A:Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payments by T/T, West Union, Paypal, Ali Trade Assurance

· Q:How do you treat quality compliant?
· A:First of all our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.

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