Local Anesthetics Lidocaine CAS 137-58-6 With Best Price

Product Details

Product Description:

    Lidocaine through reversible closing of sodium channels, blocking action potential in nerve fibers on to play the role of local anesthesia Sensory nerve fibers earlier than motor nerve fibers is blocked, so the low dose of lidocaine can play a role of selective sensory blockade Lidocaine have anti-arrhythmic effect, also belong to a class b anti-arrhythmic drugs It can reduce the ventricular rate, shorten the action potential time and the absolute refractory period, and prolong the relative refractory period. Lidocaine has rapid onset and short duration. The addition of epi nephrine to lidocaine can reduce the systemic absorption rate, thus prolonging the anesthesia time

     Local or regional analgesia is achieved through the use of peripheral nerve, osmosis, local intravenous injection and epidural injection techniques. Epidural anesthesia with an epin ephrine-free solution is generally recommended, and systemic analgesia can also be obtained by continuous intravenous infusion. Lidocaine is a first-line drug for the treatment of ventricular arrhythmias caused by acute and severe hemodynamic abnormalities. It is also effective for some supraventricular arrhythmias such as bypass mediated supraventricular tachycardia and cardioversion in acute or parasympathetic atrial fibrillation.

    It is widely used for topical anesthesia of mucous membranes (e.g., before endotracheal intubation). EMLA cream is used for topical skin anesthesia before intravenous intubation. To ensure anesthetic effect, it should be applied to the skin for 45 to 60 minutes and wrapped with an airtight dressing to promote absorption. EMLA is useful for ear vein intubation in rabbits and for intravenous intubation in young dogs and cats.

    Pharmacokinetic evaluation of lidocaine transdermal agents in dogs and cats indicates that the bioavailability of lidocaine transdermal absorption in dogs and cats is lower than in humans. The analgesic effect and clinical application of transpilidocaine in other species have not been evaluated. Intravenous infusion of lidocaine can reduce the amount of inhaled anesthetic, produce sufficient anesthetic effect and prevent injurious surgical stimulation. During general anesthesia, lidocaine is best used in combination with other analgesics to achieve balanced anesthesia. Prolonged use can lead to accumulation of lidocaine and delay resuscitation. Cats are very sensitive to the toxic effects of lidocaine during local anesthesia, so it is important to accurately calculate the dose and accurately administer it.


Why Choose Us