China High Quality CAS 34552-83-5 Loperamide HCl Hydrochloride Loperamide, Find details about China Loperamide HCl, Hydrochloride HCl from High Quality CAS 34552-83-5 Loperamide HCl Hydrochloride Loperamide
Product Name: Loperamide hydrochloride
Specification: 99%
Cas No: 34552-83-5
Einecs No: 252-082-4
Molecular formula: C29H34Cl2N2O2
Molecular weight: 513.51
Appearance: White powder
Application: Pharmaceuticals
Test Method: HPLC Purity 99%
Sample Policy: Samples available
Payment Term: L/C, TT, Western Union, D/P, Paypal
Packing Method: Vial/aluminum foil bag/carton/drum
OEM Service: Customized as guests request---Nootropics capsules
Storage: Store in cool and dry places, keep away from strong light.
Shelf life: 2 years when properly stored.
Loperamide Hcl is a white or almost white crystalline powder, can be used as antidiarrheal, or long-acting anti-diarrheal drug, used for treating acute and chronic dysentery. When overdose may occur drowsiness, constipation, muscle tension, restlessness, bradycardia and other respiratory symptoms, naloxone detoxification available, and patients were observed for at least 48 hours in order to detect inhibition of the central nervous system.
Function
The chemical structure of loperamide hydrochloride is similar to that of dinofenac, and it has no effect on the central nervous system in a therapeutic dose. The effect on intestinal smooth muscle is similar to that of opioids and diphenoxylte. It can inhibit the contraction of intestinal smooth muscle and inhibit the movement of intestinal peristalsis. By prolonging the residence time of food in the small intestine, this product can promote the absorption of water, electrolytes and glucose, and has a significant inhibitory effect on intestinal excessive secretion caused by intestinal endotoxins, but does not affect the secretion of gastric acid at the therapeutic dose.
Application
1. patients with diarrhea, especially children, frequent loss of water and electrolytes, replenish water and electrolytes is the most important therapeutic measures, children should the FDA under the guidance of a doctor.
2. for acute diarrhea, such as 48 hours after using this service, no improvement in clinical symptoms, should stop using, it is recommended to consult a doctor.
3. liver dysfunction may lead to drug overdose relative, should pay attention to the central nervous system symptoms of toxic reactions.
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