Anti-Cancer Effect API Material 99% Taxol
China Anti-Cancer Effect API Material 99% Taxol, Find details about China Taxol, Anti-Cancer from Anti-Cancer Effect API Material 99% Taxol
| Product name | Taxol | Payment | Western Union, Alibaba Trade Assurance or TT |
| Appearance | white powder | Delivery | By Couriers (DHL, FEDEX, EMS or TNT) or By Air |
| Specs | 99% | Lead Time | Within 3~5days |
| CAS | 33069-62-4 | Package | Aluminum foil bag, Paperdrum or Cartons |
Taxol/ Paclitaxel is a mitotic inhibitor used in cancer chemotherapy. It was discovered in a National Cancer Institute program at the Research Triangle Institute in 1967 when Monroe E. Wall and Mansukh C. Wani isolated it from the bark of the Pacific yew tree, Taxus brevifolia and named it 'taxol'. When it was developed commercially by Bristol-Myers Squibb (BMS) the generic name was changed to 'paclitaxel' and the BMS compound is sold under the trademark 'TAXOL'. In this formulation, paclitaxel is dissolved in Cremophor EL and ethanol, as a delivery agent. A newer formulation, in which paclitaxel is bound to albumin, is sold under the trademark Abraxane.
Function
Taxol/ Paclitaxel is now used to treat patients with lung, ovarian, breast cancer, head and neck cancer, and advanced forms of Kaposi's sarcoma. Paclitaxel is also used for the prevention of restenosis. Paclitaxel stabilizes microtubules and as a result, interferes with the normal breakdown of microtubules during cell division. Together with docetaxel, it forms the drug category of the taxanes .
Application
Taxol/Paclitaxel stabilizes microtubules and as a result, interferes with the normal breakdown of microtubules during cell division. Together with docetaxel, it forms the drug category of the taxanes.
Tests | Standards | Results | |
Appearance | white powder | Wcrystalline powder.hite, | |
Identification | A:IR absorption | Complies | Complies |
B:UV absorption | Complies | Complies | |
C:TLC | Complies | Complies | |
Melting point | 168~172°C | 169.0~170.9°C | |
Water | Not more than0.5% | 0.09% | |
Related substance | ImpurityJ(chloroacetanilide)not more than 10 ppm | 2ppm | |
Impurity K(4-aminophenol)not more than 50 ppm | 16 ppm | ||
Impurity F(4-nitrophenol)not more than 0.05% | Not detected | ||
any other impurity not more than 0.05% | 0.01% | ||
Total of other impurities not more than 0.1% | 0.02% | ||
Residue on ignition | Not more than 0.1% | 0.05% | |
Chloride | Not more than 0.014% | Less than 0.014% | |
Sulfate | Not more than 0.02% | Less than 0.02% | |
Sulfide | Conforms | Conforms | |
Heavy metals | Not more than 0.001% | Less than 0.001% | |
Free p-aminophenol | Not more than 0.005% | Less than 0.005% | |
Limit of P-chloroacetanilide | Not more than 0.001% | Less than 0.001% | |
Readily carbonizable substances | Conforms | Conforms | |
Residual solvents | Residual content of acetic acid is limited by the test of loss on dryingnot more than0.5% | 0.08% | |
Assay(anhydrous basis) | 99.0~101.0% | 99.4% | |
Conclusion: Complies with USP34/ BP2011 | |||
You Might Also Like
Low Cost 2-8mm Coffee Husk Hen Feed Press for Pakistan
Nice Design 90km Mileage Electric Scooter with Front Basket
A356 Aluminum Sand Casting Parts
3-Blade Aluminum Outboard Propeller
Mercedes Benz W639 Vito Viano Air Compressor 6393200204 6393......
Made in China Metal Zinc Alloy Soft Enamel Sport Medallion C......
10t 30t 40t Locosc Shear Beam Weighing Load Cell for Weighbr......
4.1kwh Lithium Battery Wall Mount LiFePO4 24V 160ah Deep Cyc......
A3 Size DTG Tshirt Jeans Jackets Printer for Dark Light Colo......
PVC Co-Extrusion Foam Board with Cheaper Price
Superior Popular Art Fineliner Drawing Pen with Water Proof ......