China Broad Spectrum Antineoplastic Agents High Quality Doxorubicin Preparation for Cancer with Best Price, Find details about China Antineoplastic Drugs, Powder Injections from Broad Spectrum Antineoplastic Agents High Quality Doxorubicin Preparation for Cancer with Best Price
Drug classification | Antineoplastic drugs - cytotoxic drugs - drugs that act on the chemical structure of DNA |
Use | Adriamycin is an anti-tumor antibiotic, which can inhibit the synthesis of RNA and DNA, and has the strongest inhibition on RNA. It has a wide anti-tumor spectrum, and has an effect on a variety of tumors. It is a cycle non-specific drug, and has killing effect on tumor cells of various growth cycles. It is mainly applicable to acute leukemia and is effective for both acute lymphoblastic leukemia and granulocytic leukemia. It is generally used as a second-line drug, that is, it can be considered when the first drug is resistant. Malignant lymphoma may be the drug of choice for alternate use. Breast cancer, sarcoma, lung cancer, bladder cancer and other cancers have a certain effect, and most of them are combined with other anti-cancer drugs. The main toxic reactions are leukopenia and thrombocytopenia, which can occur in 60% ~ 80% of patients; 100% of patients had varying degrees of hair loss, which could be restored after drug withdrawal. Cardiotoxicity, manifested as arrhythmia, ST-T changes, mostly appeared in 1 ~ 6 months after drug withdrawal, early application of vitamin B6 and coenzyme Q10 can reduce its cardiotoxicity; Nausea, loss of appetite; Drug extravasation may cause tissue ulceration and necrosis. In addition, the urine may appear red after medication. It is a broad - spectrum anti - tumor drug, can produce a wide range of biochemical effects on the body, has strong cytotoxicity. Its mechanism of action is mainly that the product embedded DNA and inhibit the synthesis of nucleic acid. Clinically for the treatment of acute lymphoblastic leukemia, acute myelogenous leukemia, Hodgkin's and non-hodgkin's lymphoma, breast cancer, lung cancer, ovarian cancer, soft tissue sarcoma, osteogenesis sarcoma, rhabdomyosarcoma, renal tumor, neuroblastoma, bladder tumor, thyroid tumor, chorionic carcinoma, prostate cancer, testicular cancer, gastric cancer, liver cancer, etc. |
Preparations and Specifications | Adriamycin for injection: 10mg |
Contraindications | 1. Doxorubicin can pass through the placenta, may cause abortion, so it is strictly prohibited in the first three months of pregnancy application. After pregnant women use this product, the toxic reaction to the fetus can sometimes take years to appear. 2. Doxorubicin is contraindicated during mediastinal or thoracic radiotherapy. 3. The following conditions should be prohibited: peripheral blood images with white blood cells less than 3500/μL or platelets less than 50,000 /μL, obvious infection or fever, bad fluid quality, water loss, electrolyte or acid-base imbalance, gastrointestinal obstruction, obvious anthrax or liver function damage, cardiopulmonary decompensation, varicella or herpes zoster patients. 4. Doxorubicin allergy is prohibited. |
Specification | 10mg/ piece,10 pieces to a carton |