1. Product's Name: supply nootropics NSI 189 powder NSI-189
2. CAS: 1270138-40-3
3. Puirty: 99%
4. Apperance: White Powder
5. What is NSI-189?
NSI-189 is an experimental antidepressant. In addition to treating cognitive impairments, and brain degeneration. It may induce specific brain regeneration.
Chemically speaking, NSI-189 structurally unique among other antidepressants. However, the drug has also seen increased interest in terms of its ability to stimulate nerve growth in the hippocampus. 

 

NSI-189 is neurogenic and nootropies research agent that was developed from nicotinamide and pyrazine. Randomized controlled trials have shown that it stimulates neurogenesis or neuronal cell production in the brain. In animal studies, it has also been shown to increase the volume of hippocampus by 20% thereby reversing behavioral symptoms of depression. Such studies have shown that it may be an effective treatment for depression. It is also thought to be a promising treatment for other condition including post-traumatic stress disorder (PTSD), Alzheimer's disease and age-related cognitive problems
NSI-189 successfully completed a phase I clinical trial for MDD in 2011, where it was administered to 41 healthy volunteers. A phase Ib clinical trial for treating MDD in 24 patients started in 2012 and completed in July 2014, with results published in December 2015. Neuralstem is now preparing to initiate phase II clinical studies for MDD in the first quarter of 2016, with results expected in the second half of 2017. In the two clinical studies conducted thus far, NSI-189 has shown statistically significant effectiveness in reducing depressive symptoms, has been found to be safe and well-tolerated (with no major adverse effects observed), and has been found to improve cognitive deficits in depressed patients. In addition to MDD, Neuralstem intends to pursue clinical development of NSI-189 for a variety of other neurological conditions, including traumatic brain injury, Alzheimer's disease, post-traumatic stress disorder, stroke, and natural cognitive and memory decline in aging.
1. NSI-189 may improve in behavioral responses associated with depression.
2. NSI-189 may benefit Stroke Patients Mechanisms Observed.
3. NSI-189 may enhance memory and cognition through increase neurogenesis.
4. NSI-189 may help increase Neuron Formation.
5. NSI-189 can be reversal of hippocampal atrophy. 

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