High-Quality Polysaccharide Astragalus Root Extract

China High-Quality Polysaccharide Astragalus Root Extract, Find details about China Organic Astragalus Extract Powder, Astragalus Extract Ring Astragalus Powder from High-Quality Polysaccharide Astragalus Root Extract

Basic Info.

Model NO.

Pharmaceutical Grade

Product Name

Astragalus Extract

Medium Determination Method

HPLC, UV

Application Form

Tablets, Capsules, etc.

Application Areas

Food, Health Products, Medicine

Extract Source

Astragalus

Transport Package

Cardboard or Box

Specification

1*1KG

Origin

China

Model NO.

Pharmaceutical Grade

Product Name

Astragalus Extract

Medium Determination Method

HPLC, UV

Application Form

Tablets, Capsules, etc.

Application Areas

Food, Health Products, Medicine

Extract Source

Astragalus

Transport Package

Cardboard or Box

Specification

1*1KG

Origin

China

Product Desciption

High-quality polysaccharide Astragalus root extract

Product Name:	Astragalus extract
Active ingredients:	Astragaloside IV, Astragalus Polysaccharide
Appearance:	Brownish yellow or off-white powder
Shelf Life:	2 Years

Astragalus extract Astragalus P.E [Product source] This product is the dried root extract of legume Astragalus membranaceus (Fisch.) Bge. Dry astragalus root raw materials, wash, dry, crush, 10 times the amount of water, heat and boil for extraction three times, 2 hours each time, combine the three extracts, concentrate and evaporate the water to an extract with a specific gravity of d=1.20, leave it to cool, and extract the extract Add ethanol and stir, stand for precipitation, centrifuge the precipitate, continue to add ethanol to the precipitate, stir, stand and centrifuge to obtain crude astragalus polysaccharides, remove proteins and mucous components with a mixed solvent to obtain pure astragalus polysaccharides.
It has the functions of enhancing immunity, enhancing energy, anti-fatigue, anti-mutation, protecting liver, and inhibiting osteoclasts. Astragalus polysaccharides have the effect of lowering blood lipids, that is, lowering cholesterol and triglycerides, and raising high-density lipoproteins; it can prevent and treat cardiovascular and cerebrovascular diseases, such as atherosclerosis, coronary artery disease, peripheral vascular disease, and hyperlipidemia Wait. Astragaloside IV has the effect of significantly lowering blood sugar, glycosylated hemoglobin and urine protein, and can reduce AGEs in renal cortex and serum. It shows that Astragaloside IV has an antioxidant effect, and has an inhibitory effect on aldose reductase, and it also inhibits mesangium. The effect of cell proliferation and reducing kidney hypertrophy. Adding appropriate excipients to astragaloside IV can be made into oral preparations, which are used to prevent and treat diabetic nephropathy.

High-Quality Polysaccharide Astragalus Root Extract

tem	Specification	Results	Methods
Marker Compound	70%Polysaccharides	70.25%	UV
Extract Ratio	16:1	Conform	TLC
Appearance & Color	Yellow Brown fine powder	Conform	GB5492-85
Odor & Taste	Characteristic	Conform	GB5492-85
Plant Part Used	Root	Conform
Extract Solvent	Water&Ethanol	Conform
Bulk Density	0.4-0.6g/ml	0.45-0.55g/ml
Mesh Size	80	100%	GB5507-85
Loss on Drying	≤5.0%	3.18%	GB5009.3
Ash Content	≤5.0%	1.36%	GB5009.4
Solvent Residue	Negative	Conform	GC
Residual Pesticides	Meets USP	Conform
Heavy Metals
Total Heavy Metals	≤10ppm	<3.0ppm	AAS
Microbiology
Total Plate Count	≤10000cfu/g	Conform	GB4789.2
Total Yeast & Mold	≤1000cfu/g	Conform	GB4789.15
Total Coliform	≤40MPN/100g	Not Detected	GB/T4789.3-2003
Salmonella	Negative in 25g	Not Detected	GB4789.4
Staphylococcus	Negative in 10g	Not Detected	GB4789.1

1. Effects on blood vessels and blood pressure
Astragalus has the effect of expanding blood vessels and expanding coronary arteries. Therefore, it is believed that its antihypertensive effect is the result of direct expansion of peripheral blood vessels, and has no relationship with the heart, and has no relationship with the release of histamine or the effect of adrenergic receptors. It shows that the effect of Astragalus on blood pressure is related to the central neuropeptide, renin-angiotensin-aldosterone system, carnosine releasing enzyme-carnosine system, and hydroxyproline. The antihypertensive component of Astragalus was once considered to be an alkaline substance, but later it was discovered that the roots of Astragalus plants contain aminobutyric acid, and its content is almost parallel to the antihypertensive effect, so it is considered to be an effective component for antihypertensive. In terms of vascular effects, GABA does not completely represent astragalus. Astragalus can promote the migration and proliferation of vascular endothelial cells to varying degrees, which is beneficial to the process of angiogenesis. Astragalus membranaceus saponins II, III, IV and other saponins and formononetin, verbasin and other isoflavone compounds in Astragalus membranaceus can significantly improve the deformability of hatching red blood cells, which may be important for Astragalus membranaceus to improve hemorheological indicators. Mechanism, an important part of the effect of Astragalus on human erythrocyte membrane may be to protect human erythrocyte membrane from the attack of free radicals.
2. Anti-fatigue effect
Astragalus polysaccharide 250mg/kg, 500mg/kg intraperitoneal injection, on normal mice and hydrocortisone-induced "Yang Deficiency" mice, swimming time at room temperature have a significant effect on swimming time, and increase the weight of the adrenal glands of mice under stress. Astragalus extract can significantly increase the plasma cortisol content, adrenal gland weight and lipid vacuole content in adrenal cortex cells in rats under swimming stress. Cerebral hypoxia caused by ligation of the carotid arteries on both sides has a significant antagonistic effect, which can significantly prolong the survival time of mice.
3. Long-term use of anti-aging effect
Astragalus has certain significance for preventing senile arteriosclerosis and improving senile lung function. In vitro cultured human embryonic lung diploid fibroblasts survived to 52 generations, while the cultured cells containing 0.2% astragalus extract survived to 77 generations. The changes in organelles during the aging process of the drug group and the aging ratio of the control group cells Basically the same, but the degree of change is light, and the rate of change is relatively slow, especially the Golgi complex of the cells in the drug group is particularly developed. Although the cells are senescent, they are not very senescent. Studies have proved that Astragalus has a good effect on prolonging life. As an anti-aging and prolonging drug, it is worthy of great attention and development.
4. Effects on the urinary system
Intravenous injection of astragalus injection can significantly increase the serum albumin of the rat minimally changed nephropathy model, significantly reduce the serum cholesterol, and increase the blood flow of the glomerular capillary filaments, and it also has a significant reduction in scrotal edema and ascites. The diet and mental state of the animals in the administration group are also better than those of the control group; Astragalus can significantly reduce the amount of protein in the urine; Pathological observations have also proved that the astragalus group has less disease, and this inhibitory effect on nephritis may be related to the enhanced metabolism of Astragalus. It is related to improving the nutritional status of the whole body. Astragalus can alleviate kidney disease in spontaneous lupus mice through immunomodulatory effects.
5. Hepatoprotective effect
Astragalus can protect the liver and prevent the reduction of liver glycogen. Two kinds of astragaloside ASI and SK can resist liver damage caused by D-galactosamine and acetaminophen. Astragaloside is an effective component of astragalus against hepatotoxic damage. Its mechanism is not only anti-biooxidation, but also related to metabolic regulation. Another study believes that Astragalus has a certain effect on preventing liver fibrosis.
6.Antibacterial, antiviral, and antitumor effects
Astragalus polysaccharides have obvious antagonistic effects on tuberculosis infection; other ingredients such as amino acids, alkaloids, flavonoids, etc. have been found to have significant anti-follicular stomatitis virus effects. Animal and transmutation cell experiments show that Astragalus injection has a certain blocking effect on the infection process of epidemic hemorrhagic fever and virus (EHFV) in suckling mice. Astragalus against Shigella Shigella, Bacillus anthracis, Alpha-Activated Streptococcus, Streptococcus sanguis, Diphtheria, Pseudodiphtheria, Pneumococcus, Staphylococcus aureus, Staphylococcus citrus, Staphylococcus albicans, Bacillus subtilis, etc. Has antibacterial effect.

High-Quality Polysaccharide Astragalus Root Extract

1. In the food and beverage industry, it is made into desserts, coffee, beverages, etc.
2. In the field of nutritious food, various health products are made.
3. In the cosmetics industry, as a raw material for personal care products.

High-Quality Polysaccharide Astragalus Root Extract