China Isosorbide Mononitrate Sustained-Release Tablets, Find details about China Isosorbide, Tablet from Isosorbide Mononitrate Sustained-Release Tablets
DESCRIPTION
Isosorbide Mononitrate Sustained-release Tablets, an organic nitrate and the major biologically active metabolite of isosorbide dinitrate (ISDN), is a vasodilator with effects on both arteries and veins.
Isosorbide Mononitrate Sustained-release Tablets is a white, crystalline, odorless compound which is stable in air and in solution, has a melting point of about 90°C, and an optical rotation of +144° (2% in water, 20°C).
Isosorbide mononitrate is freely soluble in water, ethanol, methanol, chloroform, ethyl acetate, and dichloromethane.
INDICATIONS AND USAGE
Isosorbide Mononitrate Sustained-release Tablets are indicated for the prevention of angina pectoris due to coronary artery disease. The onset of action of oral isosorbide mononitrate is not sufficiently rapid for this product to be useful in aborting an acute anginal episode.
DOSAGE AND ADMINISTRATION
The recommended starting dose of Isosorbide Mononitrate Sustained-release Tablets is 40 mg once daily. After several days, the dosage may be increased to 120 mg once daily. Rarely, 240 mg may be required. The daily dose of Isosorbide Mononitrate Extended-Release Tablets should be taken in the morning on arising. Isosorbide Mononitrate Extended-Release Tablets should not be chewed or crushed and should be swallowed together with a half-glassful of fluid.