roduct Name:

Piroxicam

Synonyms:

4-HYDROXY-2-METHYL-3-(PYRID-2-YL-CARBAMOYL)-2H-1,2-BENZOTHIAZINE 1,1-DIOXIDE;4-HYDROXY-2-METHYL-3-(PYRID-2-YL-CARBAMOYL)-2H-1,2-BENZOTHIAZINE 1,2-DIOXIDE;4-HYDROXY-2-METHYL-N-2-PYRIDINYL-2H-1,2-BENZOTHIAZINE-3-CARBOXAMIDE;4-hydroxy-2-methyl-n-2-pyridinyl-2h-1,2-benzothiazine-3-carboxamide 1,1-dioxide;3,4-DIHYDRO-2-METHYL-4-OXO-N-2-PYRIDYL-2H-1,2-BENZOTHIAZINE-3-CARBOXAMIDE 1,1-DIOXIDE;AURORA KA-6753;4-Hydroxy-2-Methyl-1,2-Benzothiazine-3-Carboxylic Acid Ethylester-1,1-Dioxide;Pipoxicam

CAS:

36322-90-4

MF:

C15H13N3O4S

MW:

331.35

EINECS:

252-974-3

Melting point 

198-200°C

density 

1.3664 (rough estimate)

refractive index 

1.6320 (estimate)

storage temp. 

2-8°C

solubility 

Practically insoluble in water, slightly soluble in anhydrous ethanol. It shows polymorphism (5.9).

tests carried out

limits

observations

description

a white or slightly

yellow crystalline powder

lightly yellow crystalline powder

identification

a.b.c.positive reaction

meets the requirements

water

≤0.5%

0.02%

resioue on ignition

≤0.3%

0.19%

heavy metals

≤0.005%

<0.005%

organic wolatice impurities

conforms to u.s.p.30

meets the requirements

solubility

very slightly soluble in water,in diluite acids and in most organics solvents slightly soluble in alcohol and aqueous alkaline solutions

meets the requirements

assay

contain piroxicam not less than 97.0 dereent and not more than 103.0 dereent of c15h13n3o4s

98.3%

bulk density

0.4 to 0.8g/ml

complies

granular size

100%below 25μ

complies

conclusion

it complies with u.s.p.30