Marya Pharmaceutical IV Infusion/Blowing/Filling/Sealing/Monoblock/Oral/Liquid/Forming Bfs MachineMain ApplicationPharmaceutical Plastic Bottle BFS Blowing Filling Sealing All-Closed SVP eye drop Solution Machine (BFS machine for short) is an advanced technology that integrates molding, filling and sealing under complete control, which enables liquid to be packaged in polypropylene/high-density & low-density polyethylene plastic bottle, and the whole production process automatically completes the followings in a controlled environment (aseptic environment):- Extrude plastic particles into plastic preform at high temperature.
- Then the preform is blown into a container by sterilized and filtered air.
- Filling liquid that have been sterilized and filtered.
- Tight sealing of containers after filling.
- Pharmaceutical Plastic Bottle BFS Blowing Filling Sealing All-Closed SVP eye drop Solution Machine is suitable for liquid filling in pharmaceutical, chemical and food industries with aseptic or non-aseptic packaging in plastic containers.
Steps of Blow-Fill-Sealing Process Extruding: A parison (rounded mass of molten glass) produced by extrusion of the homogenous polymer melt is introduced into the mold and the below the die.
Molding: The primary mold closes, sealing the bottom. A mandrel fits into the neck area. Using compressed air, the parison is inflated into a container.
Filling: The precisely measured sterile liquid preparation is then delivered into the container by the mandrel.
Sealing: After the mandrel withdrawal, the head mold closes and eventually forms the necessary seal via a vacuum.Performance Features S/N | Item | Description |
1 | Applied bottle range | 0.5 ml-20 ml |
2 | Capacity | 9000 /hour |
3 | Required compressed air | 0.8Mpa, 300L/min |
4 | Noise | ≤70dB |
5 | Electric capacity | 75 kw 50 Hz ac 380 V |
6 | Diameter of cooling water pipe inlet | Φ15mm |
7 | Cooling water | 3 cubic meters, 8 ºC,2 bar |
8 | Steam | preparation: 40 kg/h 2 bar, production 15 kg/h |
9 | Clean water | solution line 1m3, 2.5 bar , 15 minutes vacuum of mould: 1m3, 2.5 bar, 60 ºC,15 minutes |
10 | Net weight | 8000 kg |
11 | Overall size | 5260 X2600X3015 (long x wide x high) |
- The design, MOC, manufacturing, assembly and debugging of the BFS machine meet the requirements of the new GMP or FDA standards for drug production.
- Advanced equipment, unique and reasonable structure, stable and reliable performance.
- Applicable Specification: 0.2ml-1000ml plastic bottle (as per user's requirements).
- Production Capacity: 1000-18000BPH.
- The number of bottles made each time: 1-30 bottles/mould, can be selected based on production capacity.
- Filling Accuracy: ≤ ±1% (according to drug characteristics)
- The BFS machine is integrated with bottle-making, filling and sealing, with compact structure and occupies small area, which reduces clean workshop area and saves energy consumption of air conditioning unit, as well as investment and use cost.
- The plastic particles are plasticized by a low speed long screw extruder driven by a specially designed servo motor, which can effectively reduce thermal stress of the material and accurately control the size of bottle preforms.
- Each working cycle of the equipment can be compared and controlled automatically, with real-time feedback.
- Stainless steel 304 hopper at extrusion station of the equipment is equipped with a level switch and linked with feeding device; when the material level is getting lowered, the alarm information of "lack of material" will be displayed on man-machine interface.
- High production efficiency, stable product performance, simple and reliable operation and beautiful appearance.
- For large capacity products, the container thickness is controlled at 100 points by an advanced thickness controller, and the precision servo motor controls the gap between mold core and mold cup.
- The filling system is accurately calculated by time pressure method with high filling precision, which can meet filling range of 0.2ml-2000ml to ensure production speed.
- Certificates
Company InformationShanghai Marya Pharmaceutical Engineering&Project Co., Ltd is a professional Pharmaceutical Turnkey Project Contractor. We have 3 our own factories and more than 30 OEM factories under the quality Control of Shanghai Marya, We have a 30 year experienced professional team for doing the turnkey project from design to construction.
Our Pharmaceutical projects can be done according to international standards. We are not only a manufacturer but also a design and construction company. We can provide much better price and better technical support and service than other companies
We can design and manufacture machines based on Customer' requests, Your satisfaction is our top priority.
With 30 years of the experienced professional design team and construction team. Under the support of our factory, We can provide customers with high efficiency and quality in the project, save your time and cost.
Marya Pharmaceutical IV Infusion/Blowing/Filling/Sealing/Monoblock/Oral/Liquid/Forming Bfs Machine