China Top Quality Peptide Powder Pramlintide / Pramlintide Acetate 196078-30-5, Find details about China Pramlintide Acetate, 196078-30-5 from Top Quality Peptide Powder Pramlintide / Pramlintide Acetate 196078-30-5
Product name: Pramlintide/Pramlintide acetate
CAS No:196078-30-5
Assay: 99%
MF:C173H273N51O56S2
Molecular weight:4027.46
Appearance: white powder
Pramlintide (Symlin) is a relatively new injectable drug for diabetes (both type 1 and 2), developed by Amylin Pharmaceuticals (now a wholly owned subsidiary of AstraZeneca )Pramlintide is sold as an acetate salt.
Pramlintide is an analogue of amylin ,a small peptide hormone that is released into the bloodstream by the β-cells of the pancreas along with insulin, after a meal.Like insulin, amylin is completely absent in individuals with Type I diabetes.
Reduction in glycated hemoglobin and weight loss have been shown in insulin-treated patients with type 2 diabetes taking pramlintide as an adjunctive therapy.
By augmenting endogenous amylin, pramlintide aids in the cellular absorption and regulation of blood glucose by slowing gastric emptying, promoting satiety via hypothalamic receptors (different receptors than for GLP-1), and inhibiting inappropriate secretion of glucagon, a catabolic hormone that opposes the effects of insulin and amylin. Pramlintide also has effects in raising the acute first-phase insulin response threshold following a meal.
Specification:
Item | Standard | Result |
Appearance | White or almost white powder | White powder |
Solubility | Easily soluble in water, unsoluble in ethanol | Conform |
Solution clarity and color | Solution should be clear and colorless | Conform |
Related substances | 5'CMP 0.3% | 0.01% |
Simple impurity | 0.03% | |
Total other impurity | 0.10% | |
Ammonium | 0.05% | Conform |
Phosphate | 0.1% | Conform |
Loss on drying | ≤6.0% | 1.3% |
Heavy metals | 0.002% | Conforms |
Shelf life | 2 Years | |
Storage | Keep cool and dry in dark place |
Advantage:
Hongkong XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best service is our philosophy. We have Flexible and Untraceable payment terms. As a leading manufacture, our products have been exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Brazil, Mexico, Australia, Japan, Korea, Thailand, Indonesia, Uruguay and many other countries.
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Top Quality Peptide Powder Pramlintide / Pramlintide acetate 196078-30-5