China Factory Supply Terbinafine Hydrochloride Powder CAS 78628-80-5 Terbinafine HCl, Find details about China Terbinafine HCl, Terbinafine Hydrochloride from Factory Supply Terbinafine Hydrochloride Powder CAS 78628-80-5 Terbinafine HCl
Terbinafine hydrochloride is an antifungal, which is highly hydrophobic and tends to accumulate in hair, skin, nails, and fatty tissue.
Terbinafine hydrochloride is a white fine crystalline powder that is freely soluble in methanol and dichloromethane, soluble in ethanol, and slightly soluble in water.
Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting squalene epoxidase, an enzyme that is part of the fungal cell membrane synthesis pathway. Because terbinafine prevents conversion of squalene to lanosterol, ergosterol cannot be synthesize.
Product name | Terbinafine hydrochloride |
CAS NO. | 78628-80-5 |
MF | C21H26ClN |
Standard | Medical standard |
Appearance | White crystalline powder |
Assay | 99% |
Shelf life | 2 years |
Storage | should be stored in a well-closed container at low temperature, keep away from moisture, heat and light. |
Product name | Terbinafine Hydrochloride | ||
CAS No. | 78628-80-5 | Outer Packing | 25KG |
Standard adopted | EP8 | ||
Items of analysis | Specification | Results | |
Appearance | White or similar white powder, soluble in anhydrous ethanol and methanol, slightly soluble in acetone, extremely soluble in water | Conforms | |
Identify | Comply with the standard | Conforms | |
Impurity B | ≤0.15% | 0.001% | |
Impurity E | ≤0.05% | 0.001% | |
Unknown single impurity | ≤0.1% | 0.03% | |
Total impurity | ≤0.3% | 0.1% | |
sulphated ash | ≤0.1% | 0.05% | |
Loss on dry | ≤0.5% | 0.2% | |
ignition residue | ≤0.1% | 0.021% | |
residual solvent | isopropanol≤5000ppm;ethyl acetate≤5000ppm;trichloromethane≤60ppm | Isopropanol 5ppm;ethyl acetate 101ppm;trichloromethane not detected | |
Assay | 99-101% | 99.7% | |
Conclusion | Qualified |
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