High Quality 99% Tetracaine Base in Stock Manufacturer CAS No. 94-24-6
China High Quality 99% Tetracaine Base in Stock Manufacturer CAS No. 94-24-6, Find details about China Tetracaine Base, 94-24-6 from High Quality 99% Tetracaine Base in Stock Manufacturer CAS No. 94-24-6
Basic Information
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 389.4±27.0 °C at 760 mmHg |
| Molecular Formula | C15H24N2O2 |
| Molecular Weight | 264.363 |
| Flash Point | 189.3±23.7 °C |
| Exact Mass | 264.183777 |
| PSA | 41.57000 |
| LogP | 3.65 |
| Vapour Pressure | 0.0±0.9 mmHg at 25°C |
| Index of Refraction | 1.538 |
Specification
Items | Standard | Results of analysis |
Appearance | White to class white powder | Class white powder |
Solubility | Almost insoluble in water, soluble in dimethyl sulfoxide, slightly soluble in dichloromethane | Conforms |
Speicific rotation | +78.0°~+84.0° | +82.3° |
Ordinary impurities (Do not calculate isomer A+C) | Single impurity≤0.15% | 0.03% |
Total impurities≤1.0% | 0.09% | |
Calculate isomer | A≤0.15% | 0.02% |
B≤0.1% | Not detected | |
C≤0.1% | Not detected | |
Loss on drying | ≤0.5% | 0.31% |
Residue on ignition | ≤0.1% | Conforms |
Heavy metal | 20ppm | Conforms |
Assay | 97.5%-102.0% | 99.8% |
Conclusion :The test results conform with USP36. | ||
Description
Tetracaine, also known as amethocaine, is a local anesthetic used to numb the eyes, nose, or throat. It may also be used before starting an intravenous to decrease pain from the procedure. Typically it is applied as a liquid to the area. Onset of effects when used in the eyes is within 30 seconds and last for less than 15 minute.However, most of the tetracaine hydrochloride is still used for unconventional purposes. Such as illegal use. Especially in Brazil, tetracaine hydrochloride has been flooding in Brazil. They mixed tetracaine hydrochloride with several other drugs to make a product, and sold it in the market to achieve profiteering. Most of the tetracaine hydrochloride is flowing in the black market.
Common side effects include a brief period of burning at the site of use. Allergic reactions may uncommonly occur. Long term use is generally not recommended as it may slow healing of the eye. It is unclear if use during pregnancy is safe for the baby. Tetracaine is in the ester-type local anesthetic family of medications. It works by blocking the sending of nerve impulses.
| Anesthetic / Pain Killer | |||
| Tetracaine Base | 94-24-6 | Prilocaine hydrochloride | 1786-81-8 |
| Tetracaine hydrochloride | 136-47-0 | Proparacaine hydrochloride | 5875/6/9 |
| Lidocaine hydrochloride | 73-78-9 | Pramoxine hydrochloride | 637-58-1 |
| Linocaine Base | 137-58-6 | Procainamide hydrochloride | 614-39-1 |
| Benzocaine hydrochloride | 23239-88-5 | Ropivacaine hydrochloride | 98717-15-8 |
| Benzocaine Base | 94-09-7 | Articaine hydrochloride | 23964-57-0 |
| Procaine | 59-46-1 | Bupivacaine | 2180-92-9 |
| Procaine hydrochloride | 1951/5/8 | Mepivacaine hydrochloride/Carbocaine | 1722-62-9 |
| Prilocaine | 721-50-6 | dibucaine hydrochloride | 61-12-1 |
Application
(1) In biomedical research, tetracaine is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. Tetracaine is an allosteric blocker of channel function. At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely.
(2) Tetracaine is the T in Tac, a mixture of 5 to 12 per cent tetracaine, 5M(per myriad), a half per mille (0.5‰), or .05 per cent (1 part in 2000) , and 4 or 10 per cent hydrochloride used in ear, nose & throat surgery and in the emergemcy department where numbing of the surface is needed rapidly, especially when children have been injured in the eye, ear, or other sensitive locations.
(3) Tetracaine is synthesized from 4-butylaminobenzoic acid. The ethyl ester is formed through an acid-catalyzed esterification reaction. Base-catalyzed transesterification is achieved by boiling the ethyl ester of 4-butylaminobenzoic acid with excess 2-dimethylaminoethanol in the presence of a small amount of sodium ethoxide.
Our Company
Our company is committed to the development of international market , our products are mainly exported to many countries and regions, such as Europe, America, South-east Asia, the Middle East and Africa etc. With our constant efforts and good service, We sincerely hope to establish long-term cooperation and common development with our customers.
Shipping Advise: Service
------Suitable for under 50kg, Fast:3-7 days.
High cost; Door to door service. Easy to pick up the goods.
2. By Air
------Suitable for more than 50 kg, Fast:3-7 days,
High cost, airport to airport. professional broker needed.
3. By sea
------Suitable for more than 500kg. Slow: 5-45 days,
Low cost. Port to Port, professional broker needed.
Service:
1. Any inquiries will be replied within 24 hours.
2. Dedication to quality, supply & service.
3. Strictly on selecting raw materials.
4. OEM/ODM Available.
5. Reasonable & competitive price, fast lead time.
6. Sample is available for your evaluation & formulation development.
Advantage:
1. Faster delivery: Sample order in stock and 3-7 days for bulk production.
2. We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder.
Q&A
1.Will you supply samples for test the quality?
We'd like to offer the samples for the quality evaluation,the shipping cost is borne by customers.
2.What is the payment term? 
T/T, Western Union or L/C and so on.
3.What is your package?
Powder: PE bag, glass bottle or PTFE bottle for inner packing
Liquid: glass bottle or PTFE bottle for inner packing
Bulk order: Fiber drum or steel drum.
4.What is your delivery term and delivery period?
FOB, CIF, etc. You can choose the one which is the most convenient or cost effective for you.
The sample within 5 days, and bulk order within 7 days.
5.How to delivery by express?
A: Parcel will be shipped out in 3 working days after payment. Usually we use EMS, ePacket, Fedex, DHL, TNT and USA Domestic mixed shipping and so on.
6.Is there a discount?
A: Yes, for larger quantity, we always support with better price.
7.What's your MOQ?
A: For the high value product, our MOQ starts from 1g and generally starts from 10gs. For other low, price product, our MOQ starts from 100g and 1kg.
8.How to make orders?
A: Send inquiry to us,we do the offer. Payment via Western Union, Moneygram, Bank Account ect.. Then we will arrange shipping. After delivery we will offer tracking No...
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