China GMP Factory Direct Supply 99% Purity Tetracaine HCl / Tetracaine Hydrochloride Powder CAS: 136-47-0

China GMP Factory Direct Supply 99% Purity Tetracaine HCl / Tetracaine Hydrochloride Powder CAS: 136-47-0, Find details about China Tetracaine HCl, Tetracaine HCl Powder from China GMP Factory Direct Supply 99% Purity Tetracaine HCl / Tetracaine Hydrochloride Powder CAS: 136-47-0

Appearance
White Powder
CAS
136-47-0
Grade
Medicine Grade
Mf
C15h25cln2o2
MW
300.82
Trademark
WHOK
Transport Package
Discreet and Disguised
Specification
As your request
Origin
China
HS Code
3001200020
Appearance
White Powder
CAS
136-47-0
Grade
Medicine Grade
Mf
C15h25cln2o2
MW
300.82
Trademark
WHOK
Transport Package
Discreet and Disguised
Specification
As your request
Origin
China
HS Code
3001200020

Product Description

Product Name: Tetracaine hydrochloride
Synonyms: L AND OCAIN HYDROCHLORIDE;
CAS: 136-47-0
MF: C15H25ClN2O2
MW: 300.82
EINECS: 205-248-5
Product Categories: Amines;Heterocycles;Intermediates & Fine

Product Introduction

Tetracaine (INN, also known as amethocaine; trade name Pontocaine. Ametop and Dicaine) is a potent local anesthetic of the ester group. It is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia.
In biomedical research, tetracaine is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores.

Tetracaine is an allosteric blocker of channel function. At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely.

In the manufacture of pharmaceutical preparation for external use, to relieve the pain of drugs or medication lesions pain.

Product Usage

Tetracaine HCl is synthesized from 4-butylaminobenzoic acid. The ethyl ester is formed through an acid-catalyzed esterification reaction. Base-catalyzed transesterification is achieved by boiling the ethyl ester of 4-butylaminobenzoic acid with excess 2-dimethylaminoethanol in the presence of a small amount of sodium ethoxide.

COA

 

ItemsQUALITY STANDARDSRESULTS
DescriptionWhite or almost white crystalline powderWhite crystalline powder
SolubilityMatching with the working standardComplies
IdentificationA.By IR, To match with working standardComplies
B: To 10ml of solution S add 1ml of ammonium thiocyanate solution R.A white,crystalline precipitate is formed which,after recrystallisation from water R and drying at 80ºC for 2h,melts at about 131ºCComplies
C. To about 5mg add 0.5ml of fuming nitric acid R .Evaporate to dryness on a water-bath,allow to cool and dissolve the residue in 5ml of ace R.Add 1ml of 0.1M alcoholic potassium hydroxide.A violet colour developsComplies
 D. Solution S gives reaction of chlorides.Complies
PH4.5~6.55.78
Residual SolventsConform to standardComplies
ClarutySolution should be clearComplies
Related SubstancesConform to standardComplies
Heavy metals≤10ppm<10ppm
Loss on drying≤1.0%0.87%
Resiue on ignition≤0.1%0.05%
Melting range148ºC147.5ºC~150.8ºC
Assay(*)99%~101.0%100.40%
ConclusionThe Sample Complies With Specification of EP8

Tags

Tetracaine HCL Powder,Tetracaine Hydrochloride Powder,Tetracaine HCL Manufacturer,Tetracaine HCL Dosage,Tetracaine HCL Supplier,136-47-0,Local Anesthetic Drugs

Our Market

China GMP Factory Direct Supply 99% Purity Tetracaine HCl / Tetracaine Hydrochloride Powder CAS: 136-47-0

Shipment Way

China GMP Factory Direct Supply 99% Purity Tetracaine HCl / Tetracaine Hydrochloride Powder CAS: 136-47-0

Our Advantages

China GMP Factory Direct Supply 99% Purity Tetracaine HCl / Tetracaine Hydrochloride Powder CAS: 136-47-0China GMP Factory Direct Supply 99% Purity Tetracaine HCl / Tetracaine Hydrochloride Powder CAS: 136-47-0China GMP Factory Direct Supply 99% Purity Tetracaine HCl / Tetracaine Hydrochloride Powder CAS: 136-47-0