Description
 

Estradiol is a white or milky white or non-crystalline powder. It is soluble in dioxan e and aceton e, slightly soluble in ethanol, but insoluble in water. Estradiol is an intermediate between estradiol valerate and estradiol benzoate, and is an estrogenic drug. It can be used to treat uterine Chemicalbook functional bleeding, primary amenorrhea, menopausal syndrome and prostate cancer. Estradiol can promote and regulate the normal growth of female sexual organs and secondary sexual characteristics, promote the maturation and growth of mammary ducts, and help positioning. Estradiol can also be used in biochemical research.

Function

Estradiol (E2 or 17β -estradiol) (also oestradiol) is a sex hormone.Estradiol is the predominant sex hormone present in females. It is also present in males,And at a higher level because it is being constantly produced.In females it is only produced 3 out of 30 days of the cycle. It represents the major estrogen in humans.Estradiol has not only a critical impact on reproductive and sexual functioning, but also affects other organs including the bones.Estrogens direct the development of the female genotype in embryogenesis and at puberty. Estradiol is the major estrogen secreted by the premenopausal ovary. Estradiol benzoate is an estradiol analog which contains a benzyl ester at the C-3 position and is often used in combination with a progestin to induce estrus in domestic livestock. This compound binds to the human and murine estrogen receptor α (ERα), and chicken ER with IC50 values in the range of 22-28 nM. This reflects a 6-10 fold reduction in binding affinity compared to estradiol.