China CAS 738-70-5 Trimethoprim Fast Shipment, Find details about China CAS 738-70-5 Trimethoprim, Trimethoprim from CAS 738-70-5 Trimethoprim Fast Shipment
Introduction:
Chemical Name: Trimethoprim (TMP)
Other name:
Abaprim;5-((3,4,5-trimethoxyphenyl)methyl)-2,4-pyrimidinediamine;5-(3,4,5-trimethoxybenzyl)-2,4-diaminopyrimidine
CAS: 738-70-5
EINECS No.: 212-006-2
Formula: C14H18N4O3
Molecular Weight: 290.32
Purity: 99.8%
Appearance: White or yellowish-white powder
BP/USP Pharmaceutical
Function:
antibacterial drug efficiency, separate for respiratory tract infections, urinary tract infections,intestinal infections and other illnesses. Range and similar antibacterial sulfonamides, in combination with sulfa drugs or in combination with antibiotics, can significantly improve drug efficacy. For respiratory tract infections, senile chronic bronchitis, dysentery, urinary tract infection, pyelonephritis, enteritis, typhoid, gonorrhea, and some of the specific disease and other inflammation.
Application:
Cure pneogaster infection, chronic senile bronchitis, bacillary dysentery, urinary tract infection, pyelon-dphristis, enteritis typhoid, gonorrhea and some specific lesion etc
Specification:
Items | Standard | Results | ||
Appearance | White or yellowish-white powder | White powder | ||
Solubility | Very slightly soluble in water, slightly soluble in alcohol. | Very slightly soluble in water, slightly soluble in alcohol. | ||
•Identification | ||||
A: Melting point | 199-203 | 201.0-201.4 | ||
B: Specific absorbance | Max.287nm: 240-250 | 243 | ||
C: IR-spectrum | Complies with reference spectrum | Complies with reference spectrum | ||
D: Chemical reaction | Green fluorescence at 365nm | Green fluorescence at 365nm | ||
Appearance of solution | Not more intensely colored than Reference Solution BY7 | Less intensely colored than reference solution BY7 | ||
Related substances | ||||
Method A by HPLC: |
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| ||
Impurity F | ≤0.1% | 0.05% | ||
Any single impurity | ≤0.1% | <0.1% | ||
Total impurities | ≤0.2% | <0.2% | ||
Method B by HPLC: |
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| ||
Any single impurity | ≤0.1% | <0.1% | ||
Total impurities | ≤0.2% | <0.2% | ||
Heavy metals | ≤20ppm | < 20ppm | ||
Residual methanol | ≤3000ppm | Not detected | ||
Residual DMSO | ≤5000ppm | Not detected | ||
Residual acetic acid | ≤5000ppm | Not detected | ||
Impurity K(aniline) by GC | ≤5ppm | Not detected | ||
Loss on drying | ≤0.5% | 0.3% | ||
Sulphated ash | ≤0.1% | 0.02% | ||
Assay | 98.5-101.0% | 99.71% | ||
Particle size | 100% pass 300 mesh | 100% pass 300 mesh |