CAS 86386-73-4 Medicine Grade API Fluconazole

China CAS 86386-73-4 Medicine Grade API Fluconazole, Find details about China Fluconazole, Fluconazole Powder from CAS 86386-73-4 Medicine Grade API Fluconazole

Basic Info.

Model NO.

Fluconazole

C13h12f2n6o

306.271

Standard

Ep/USP

Einecs

627-806-0

Type

Antibiotic and Antimicrobial Agents

Shelf Life

24 Months

Storage

Coll Dry Place

Trademark

HNB

Transport Package

1kg/Bag, 25kg/Drum

Specification

Fluconazole

Origin

China

Model NO.

Fluconazole

C13h12f2n6o

306.271

Standard

Ep/USP

Einecs

627-806-0

Type

Antibiotic and Antimicrobial Agents

Shelf Life

24 Months

Storage

Coll Dry Place

Trademark

HNB

Transport Package

1kg/Bag, 25kg/Drum

Specification

Fluconazole

Origin

China

Product Desciption

CAS 86386-73-4 Medicine Grade API Fluconazole

Product Name	Fluconazole
Apperance	White Powder
Specification	99% Pure
Cas No.	86386-73-4
M.F.	C13H12F2N6O
Place of Origin	China
Storage and Handling	Store in a cool and dry place, keep away from direct strong and heat.
Packing	Customer Requirement
Shelf life	Two years if sealed and store away from direct sun light.

Fluconazole is a novel triazole antifungal agent with a broad spectrum of antifungal activity. It is a systemic antifungal product with a highly selective inhibition of fungal cytochrome P-450-dependent enzymes. It is also a potent and specific inhibitor of fungal alcohol synthesis.Clinically, it is mainly used for vaginal candidiasis, thrush, attrophic oral candidiasis, fungal meningitis, pulmonary fungal infection, abdominal infection, urinary tract infection and skin fungal infection, etc.

The main indications for fluconazole are as follows:

1. Systemic candidiasis: includes candidiasis, disseminated candidiasis, and other forms of invasive candidiasis, such as peritoneal, endocardial, pulmonary, and urinary tract infections.It can also be used in patients with malignant tumors, patients in special care, patients receiving radiation, chemotherapy, or immunosuppressive therapy, or those who are affected by other factors that are susceptible to candida infection.It can also be used for bone marrow transplant patients to receive cytotoxic drugs or radiation therapy, to prevent the occurrence of candida infection.

2. cryptococcosis: including cryptococcal meningitis and other parts (such as lung, skin) cryptococcal infection.It can be used for patients with normal immune function, AIDS patients and patients with organ transplantation or other causes of immunosuppression.
AIDS patients may take this product for maintenance therapy to prevent the recurrence of cryptococcosis.

3. Mucosal candidiasis:
including oropharyngeal, esophagus, non-invasive bronchial and other mucosal candidiasis, pulmonary candidiasis, candidiuria, skin mucosa and chronic atrophic oral candidiasis.It can be used in patients with normal or impaired immune function.

4. Fluconazole can also replace itraconazole in the treatment of blastomycosis and histoplasmosis.

5. Acute or recurrent vaginal candidiasis.

6. For patients with leukemia and other malignant tumors prone to fungal infection due to chemotherapy or radiotherapy, this product can be used for preventive treatment.

7. coccidiomycosis.

8. dermatomycosis: including tinea body, tinea hand, tinea pedis, tinea versicolor, tinea capitis, tinea fingernail onychylosis and other skin fungal infections.

9. Fluconazole can be used for the treatment of skin pigmentation mycosis.

Product Function

Fluorotriazole broad-spectrum antifungal agents, similar to ketoconazole in antibacterial spectrum, with long effect, effective for deep fungal infections, strong antifungal effect and good oral absorption.It is mainly used for candidiasis and cryptococcosis and is also effective against oropharyngeal candidiasis in cancer patients.

Product Application
Fluorotriazole antifungal agents have similar antibacterial spectrum to ketoconazole and stronger antibacterial activity than ketoconazole.The mechanism of action is inhibition of ergosterol synthase, a necessary component of fungal cell membrane, which hinders ergosterol synthesis Chemicalbook, damages the integrity of fungal cell wall, and inhibits its growth and reproduction.This product has strong antibacterial activity to candida albicans, large and small spore bacteria, cryptococcus neoformans, tinea epidermis and histoplasma capsulatum, etc.