Levocetirizine dihydrochloride,(R)-[2-[4-[(4-chlorophenyl) phenylmethyl]-1-piperazinyl] ethoxy] acetic acid dihydrochloride, (Xyzal) is awhite, crystalline powder and is water soluble. This R-enantiomer is has a 30-fold higher affinity than the S-enantiomer,and dissociates more slowly from H1-receptors.

Pharmacologically, it displays the same receptor and CNSselecitivity profile as the racemate, cetirizine,and thus the same therapeutic advantages. Levocetirizine isindicated for the relief of symptoms associated with allergicrhinitis (seasonal and perennial) in adults and children 6 yearsof age and older and for the treatment of the uncomplicatedskin manifestations of chronic idiopathic urticaria in adultsand children 6 years of age and older. Its pharmacokineticsand clearance profile are essentially the same as the racemate,cetirizine .

Usage:It is used to treat seasonal allergic rhinitis, perennial allergic rhinitis, allergic conjunctivitis, and chronic idiopathic urticaria.

Application&Function

Levocetirizine hydrochloride is a medication prescribed to treat symptoms of seasonal allergies and hives. These symptoms can include sneezing, a runny nose, and watering eyes, as well as itching and rashes. This antihistamine can help alleviate allergy symptoms by inhibiting the actions of the chemical histamine in the body.

Specification