Vortioxetine hydrobromide is a novel bisaryl thioalkylamine antidepressant co-developed by Takeda Japan and Lingbei, Denmark. It is used in the treatment of depression and anxiety disorders. In September 2013, it was awarded the United States. The FDA approved the listing for the treatment of major depressive disorders in adults. In October of the same year, vodisidinetin's marketing authorization application (MAA) received positive opinion from the European Medicines Agency (EMA) Human Medicine Products Committee (CHMP), 2013 In December of this year, the EMA European Commission granted wattacetin to its sales rights throughout the EU. There are four specifications for vortioxetine: 5 mg, 10 mg, 15 mg, and 20 mg.

Valticetine hydrobromide is considered to be a novel multi-model antidepressant drug. In vitro studies have shown that it can antagonize 5-HT3, 5-HT7 and 5-HT1D receptors, activate 5-HT1A receptors, and partially activate 5- HT1B receptors and inhibit 5-HT transport.

Vortioxetine is another antidepressant drug that was developed to replace patent expired drug citalopram.





Wuhan Vanz Pharm Inc., which is specialized in custom synthesis and R&D, is located in Wuhan, China. our main products are indacaterol, carmoterol etc. We have established long-term cooperation with Shanghai Institute of Organic Chemistry, WuhanUniversity etc. As a special team in organic chemistry and medicinal chemistry, we support the technology of R&D on new product.We have strong advantages on the process research and product R&D, pay attention to researching and developing new technologywhich is self-owned intellectual property right. We are special at developing Drug for the respiratory, antidepressant, antivirus.We have completed R&D of more than 20 APIs and intermediates after the company founded.

R&D
Our R&D center covers an area of 1000 square meters, with four synthesis labs, one scale-up pilot labs and one analytical lab. Thelab is equipped with complete laboratory facilities and equipment. We have a professional research team of highly qualified andexperienced chemists. most of our R&D team are Master and higher. With their effort, we quickly transfer the science fruit intoproduction. Our manufacturing site is located in Wuhan which is equipped with 100L~5000L reactors; we can offer one-stop services from R&D to commercial production. (Normal reaction/ High-pressure reaction/ Catalytic reaction/ Low-Temperature reaction)