Milrinone
Appearance:hoar crystalline powder
Cas:9041-08-1
Instuction:Milrinone, commonly known and marketed under the brand name Primacor, is a medication used in patients who have heart failure. It is a phosphodiesterase 3 inhibitor that works to increase the heart's contractility and decrease pulmonary vascular resistance. Milrinone also works to vasodilate which helps alleviate increased pressures (afterload) on the heart, thus improving its pumping action. While it has been used in people with heart failure for many years, recent studies suggest that milrinone may exhibit some negative side effects that have caused some debate about its use clinically.
Overall, milrinone supports ventricular functioning of the heart by decreasing the degradation of cAMP and thus increasing phosphorylation levels of many components in the heart that contribute to contractility and heart rate. Milrinone use following cardiac surgery has been under some debate because of the potential increase risk of postoperative atrial arrhythmias. However, in the short term milrinone has been deemed beneficial to those experiencing heart failure and an effective therapy to maintain heart function following cardiac surgeries. There is no evidence of any long term beneficial effects on survival.
Stability:Stable. Incompatible with strong oxidizing agents.
Storge:2-8ºC
Our manufacturer has introduced ISO9001 quality management system certification, realizing the whole process control through product design, raw
material procurement, production process, quanlity assurance, product sales to after service;
Our manufacturer has fully implemented GMP/FDA/CEP management, GMPDA/CEP certifications are available.
Our manufactuer always takes innovation as the core, and attaches great importance to the improvement of its R & D comprehensive strength.
1. We can offer you sample for testing.
2. We can pack the material as per your requirement.
3. We can provide you TP documents along shipment.
4. We can accept your audit if necessary near future.
5. We can offer the material as per your specification.
6. We can customize the product as per your specification.
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