Products

Microbial Culture Bioreactor

China Microbial Culture Bioreactor, Find details about China Industrial Microbiology, Fermentation Tank from Microbial Culture Bioreactor

Model NO.
200L
Condition
New
Warranty
1 Year
Trademark
FUL
Transport Package
Exportable Wooden Box
Specification
custom made
Origin
China Fujian
HS Code
84798999
Model NO.
200L
Condition
New
Warranty
1 Year
Trademark
FUL
Transport Package
Exportable Wooden Box
Specification
custom made
Origin
China Fujian
HS Code
84798999
Product Description

 

 

 

Microbial Culture Bioreactor
Feature description:
The cell reactor is used to complete the cell culture process from seed expansion to production culture, including the transfer and mixing of various materials, the precise control and display of temperature, pressure, pH, DO (dissolved oxygen), foam, liquid level and volume as well as the amount of alkali replenishment, replenishment volume, replenishment rate, the aseptic filtration, measurement and display of incoming air, oxygen, carbon dioxide and nitrogen (if any), the good control of condensation, heating and aseptic filtration of exhaust , the necessary online cleaning and sterilization operations during the production process, etc.
The ability to meet the temperature, pressure, pH, DO, foam and other requirements of existing production processes at the maximum working volume. The control of liquid level, cell density increased 5-15 times in 48h-72h after inoculation of CHO cells, with densities of 2.0×105Cells/mL-4.0×107Cells/mL. All parameters of the tank can be controlled.
The cell culture process from seed expansion to production culture, including the transfer and mixing of various materials, the precise control and display of temperature, pressure, pH, DO (dissolved oxygen), foam, liquid level and volume, as well as the amount of alkali replenishment, the amount of replenishment, the rate of replenishment, the aseptic filtration, measurement and display of added air, oxygen, carbon dioxide, nitrogen (if any); good control of the condensation, heating and aseptic filtration of emissions; the necessary online cleaning and sterilization operations in the production process.
Product Parameters
Speed control

Intelligent automatic PID control, pulse width modulation rare earth DC motor +

 gearbox, stirring speed: 50-1000rpm, variable speed, accuracy ± 5 ‰

DO control

PID intelligent automatic control, imported Swiss electrodes and cables,

measuring range: 0-150%, control accuracy: ± 3%. Resolution 0.1%,

according to the fermentation process controlled by fermentation time

sequence(DO automatic variable control, multi-segment), can associated

control with speed, air flow, pressure, feeding and other parameters

PH control

Intelligent PID automatic control, imported Swiss electrodes and cables, two peristaltic pumps.

Display range: 0.00 to 14.00 ± 0.01, control range: 2.00 to 12.00 ± 0.02.

Online detection, automatic alarm, automatically add acid/alkali solution by peristaltic pump 

pH value curve analysis, acid/alkali volume curve analysis, quantitative analysis batch report,

The cumulative amount of acid/alkali added display records,

Control the fermentation process by fermentation time sequence

(pH automatic variable controller, multi-segment)

Temperature control

Intelligent PID automatic control,  thermostatic bath + PT100 temperature

sensor + electric heating + solenoid valve range; cooling water

temperature +3 -60 ºC, accuracy of ± 0.2 ºC, 0.1 ºC resolution

Feeding control

Air ratio control switch can be set to 1-100%, automatic flow and measured.

Supplement feeding amount curve analysis, the amount accumulated,

display records, save of batch reports analyze.

Control the fermentation process segment by fermentation time

sequence(automatic feeding variables, multi-segment) .

Dedicated pins and needles feeding sets, to ensure safe operation of feeding.

Defoaming control

Intelligent PID automatic control, electrode detection, adding defoamer by

peristaltic pump, sensitivity 100-100000Ω, can supplement quantitative and timing.

VentilationManual adjustment, the flow meter measure, ventilation 1: 1-2VVM
PressureManual adjustment, pressure gauge measure ,the range 0-0.2MPa
SterilizationManual adjustment, the program assisted sterilization, sterilization reign / off-site.
Control system

Based on the German scene controller S7-200 Siemens programmable logic

controller series as the core.  Imported 5.7 "true color touch screen.

Independent control software, matte stainless steel control cabinet.

Data processing can be performed and the curve displayed

Data A / D or D / A conversion, data capture to display, each control loop tuning

PID operation and setpoint control, timing control and host communications.

Exhaust

Stainless steel exhaust condenser exhaust
Function

PC remote control 

Automatic sterilization 

Exhaust O2, CO2 detection 

Oxidation-reduction detection 

Automatic ventilation 

Automatic tank pressure

Tank Weighing 

Feeding Weighing

Online precisely calculated important parameters 

OUR, CER, RQ, KLα, etc.,which indirectly reflect 

the changes in cell metabolism stream.

 

Features

1. With low shear force and good mixing effect, it can meet the requirement of free suspension cell culture. 
2. Equipped with aself-cleaning liquid change tube, which can meet the requirement of up to 5 times the culture volume flow per day under continuous culture conditions without clogging. 
3. Unique bubble-free ventilation device. Completely solve the damage of air bubbles to cells under various culture conditions, and at the same time reach the oxygen transfer rate of 10ml/L/Hr to meet the requirements of high density culture. 
4. Innovative sterilization sampling device. In any case, you can sample, observe, and test.
5. All connections are hygienic, simple and convenient.
6. Combination of surface ventilation and deep ventilation.
7. The open design of pipes and pipe racks is convenient for use and maintenance.
8. The control system uses industrial programmable logic control elements from Siemens. The system is open and can replacedamaged modules online. 
9. The parameter control adopts deviation tolerance control, and the control parameters are stable without fluctuation. 
10. Two stable reference points are adopted for stability, and the temperature is stable and reliable.
11. The stirring speed can be set as a function of time to meet the requirements of stirring speed in different cultivation periods. 
12. The software system has the function of automatically diagnosing each subsystem, which is convenient for overhaul and maintenance. 
13. Control is based on Windows Ce operating system, simple and easy to learn. 
14. Comply with GMP/cGMP requirements.
 
Certifications

 

Microbial Culture Bioreactor
Microbial Culture Bioreactor
Microbial Culture Bioreactor
Our Advantages

 

Microbial Culture Bioreactor
FUL can provide a full set of services for amoxicillin production line, azithromycin production line, insulin production line, animal and plant bacterial fermentation, vaccine cultivation (foot-and-mouth disease vaccine, avian influenza vaccine) and production, including tank design, tank production, on-site installation, on-site operation and commissioning , Personnel training, after-sales service and so on. The overall service ensures that the production line is convenient, efficient, safe and reliable, and that the final product quality is qualified and the drug effect is good, which can be directly filled into commodities or stored. The company has completed many similar vaccine projects in China and has enough experience and technology to help improve the process design and ensure the success of the project.
 

Company Profile:

Fuzhou FUL Fluid Equipment & Pharmaceutical Co., Ltd is a comprehensive enterprise which integrates R & D, production and construction of pharmaceutical production equipments, development and transfer of biotechnology, and cooperative production and sales of drugs and vaccines. The self-developed pharmaceutical production equipment branded FUL has been put into operation in many well-known pharmaceutical enterprises such as SINOPHARM, CSPC and also cooperates with many well-known pharmaceutical enterprises in production and sales, including pharmaceutical intermediates, APIs and finished drug preparations.

Fuzhou FUL Fluid Equipment & Pharmaceutical Co., Ltd business radiates to all levels, including direct supply cooperation with government departments and industry representatives, as well as establishing supply cooperation relationship with retail industry. We supply high quality, safe and effective medicines and medical equipment to governments, hospitals, clinics and licensed pharmacies in different countries with timely and effective services at reasonable prices.

At present Fuzhou FUL Fluid Equipment & Pharmaceutical Co., Ltd has the Sinopharm authorization to sell its intermediates and APIs,and has the Sinopharm of CSPC & HUABEI PHARM sell its finished drug preparations;then FUL is the only manufacture in China which can supply the complete service from pharmaceutical produciton lines,intermediates and APIs to finished drug preparations and vaccines.Then we are seeking the professional pharmaceutical enterprices to work together for further cooperations. 
FAQ

 

1. Are you a factory or a trading company?

Answer: We are a factory.

 

2. What is MQQ?

Answer: 1 unit.

 

3. Do you provide overseas services?

Answer: Yes, we can send engineers overseas.

 

4. Can we visit your factory?

Answer: Yes, you are very welcome.

 

5. What is your delivery time?

Answer: 2 weeks to 3 months. It depends on the size and quantity.
 
 


 

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