Anti-Diabetic CAS 21187-98-4 Gliclazide Purity Gliclazide Raw Powder Gliclazide
China Anti-Diabetic CAS 21187-98-4 Gliclazide Purity Gliclazide Raw Powder Gliclazide, Find details about China Gliclazide, Pharmaceutical Intermediate Gliclazide from Anti-Diabetic CAS 21187-98-4 Gliclazide Purity Gliclazide Raw Powder Gliclazide
Basic Info.
Model NO.
D-sung Gliclazide
Product Name
Gliclazide
Name
Gliclazide Powder
Appearance
White Powder
Color
White
Grade
Pharmaceutical Grade
Assay
HPLC 99%
Application
Anti-Diabetic
Specific
COA
Test Method
HPLC
Shelf Life
2 Years
CAS No.
21187-98-4
Mf
C15h21n3o3s
MW
323.41054
Melting Point
163-169ºC
Density
1.35
Trademark
D-sung
Transport Package
Negotiable
Specification
99%
Origin
Shaanxi Xi′an
Model NO.
D-sung Gliclazide
Product Name
Gliclazide
Name
Gliclazide Powder
Appearance
White Powder
Color
White
Grade
Pharmaceutical Grade
Assay
HPLC 99%
Application
Anti-Diabetic
Specific
COA
Test Method
HPLC
Shelf Life
2 Years
CAS No.
21187-98-4
Mf
C15h21n3o3s
MW
323.41054
Melting Point
163-169ºC
Density
1.35
Trademark
D-sung
Transport Package
Negotiable
Specification
99%
Origin
Shaanxi Xi′an
Product Desciption
Anti-Diabetic CAS 21187-98-4 Gliclazide Purity Gliclazide Raw Powder Gliclazide
| Product name | Gliclazide |
| Appearance | White powder |
| CAS NO. | 21187-98-4 |
| MF | C15H21N3O3S |
| MW | 323.41054 |
Gliclazide is an oral antihyperglycemic agent used for the treatment of diabetes mellitus type II. It belongs to the sulfonylurea class of secretagogues, which stimulates β cells of the pancreas to release. Gliclazide binds to the β cell sulfonyl urea receptor (SUR1), further blocking the ATP sensitive potassium channels. Therefore, the potassium efflux substantially decreases, causing depolarization of the β cells. Then the voltage-dependent calcium channels in the β cell are open, resulting in calmodulin activation, which in turn leads to exocytosis of containing secretorty granules. Recent studies have also shown that gliclazide can effectiveimprove anti-oxidant status and nitric oxide-mediated vasodilation in Type 2 diabetes and protect pancreatic beta-cells from damage.
1. For adults with type 2 diabetes, diabetes associated with obesity or vascular lesions.
2. Hypoglycemic agents. It can be used for the treatment of non- dependent diabetes mellitus.
3. Hypoglycemic agents, non-dependent diabetes mellitus.
1. For adults with type 2 diabetes, diabetes associated with obesity or vascular lesions.2. Hypoglycemic agents. It can be used for the treatment of non- dependent diabetes mellitus.
3. Hypoglycemic agents, non-dependent diabetes mellitus.
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