Loperamide Hcl is a white or almost white crystalline powder, can be used as antidiarrheal, or long-acting anti-diarrheal drug, used for treating acute and chronic dysentery. When overdose may occur drowsiness, constipation, muscle tension, restlessness, bradycardia and other respiratory symptoms, naloxone detoxification available, and patients were observed for at least 48 hours in order to detect inhibition of the central nervous system.

The chemical structure of loperamide hydrochloride is similar to that of dinofenac, and it has no effect on the central nervous system in a therapeutic dose. The effect on intestinal smooth muscle is similar to that of opioids and diphenoxylate. It can inhibit the contraction of intestinal smooth muscle and inhibit the movement of intestinal peristalsis. By prolonging the residence time of food in the small intestine, this product can promote the absorption of water, electrolytes and glucose, and has a significant inhibitory effect on intestinal excessive secretion caused by intestinal endotoxins, but does not affect the secretion of gastric acid at the therapeutic dose.
1. Used as an antidiarrheal medicine.
2. Treat diarrhea.