Veterinary Drug Doramectin Powder CAS 117704-25-3 99% Doramectin

China Veterinary Drug Doramectin Powder CAS 117704-25-3 99% Doramectin, Find details about China Doramectin Material, Doramectin Powder from Veterinary Drug Doramectin Powder CAS 117704-25-3 99% Doramectin

Basic Info.

Model NO.

Wucine-2066

C50h74o14

Application

Antiparasitic

Molecular Weight

899.11

Purity

99%

Appearancr

White Powder

Certificate

ISO, GMP

Test Method

HPLC

Brand Name

Wucine

Sample

Available

Transport Package

1kg/Bag, 25kg/Drum

Origin

Shaanxi, China

HS Code

29419090

Model NO.

Wucine-2066

C50h74o14

Application

Antiparasitic

Molecular Weight

899.11

Purity

99%

Appearancr

White Powder

Certificate

ISO, GMP

Test Method

HPLC

Brand Name

Wucine

Sample

Available

Transport Package

1kg/Bag, 25kg/Drum

Origin

Shaanxi, China

HS Code

29419090

Product Desciption

Veterinary Drug Doramectin Powder CAS 117704-25-3 99% Doramectin

Doramectin is a new type of abamectin antiparasitic drug. Its anthelmintic effect is similar to that of ivermectin. It can inhibit the transmission of nerve impulses between nerves and muscles, and paralyze the parasites from the host and die. , But due to the high blood concentration of doramectin in the body, the elimination is slower (the half-life of doramectin is 5.7d and the half-life of ivermectin is 4.2d), and the drug effect is maintained for a longer time, so the deworming effect is better , And there is no allergic reaction, it is safer to use.

Product Name	Doramectin
CAS	117704-25-3
Appearance	White powder
MF	C50H74O14
Molecular Weight	899.11
Purity	99%
Shelf Life	24 Months

Veterinary Drug Doramectin Powder CAS 117704-25-3 99% Doramectin

Items	Specification	Result
Appearance	White powder	White powder
Identification	HPLC:The retention time of major peak of test solution should correspond to that of reference solution	Conforms
Identification	IR:Sample spectrum corresponds to that of standard spectrum	Conforms
Appearance of solution	The solution is clear and not more intensely colored than reference solution BY6	Conforms
Related Substance	Avermectin NMT 2.0%	0.008
Related Substance	Total impurities NMT 5.0%	0.039
Residual Solvents	Ethanol NMT 30000ppm	360ppm
Residual Solvents	Acetone NMT 5000ppm	140ppm
BHT	NMT 2000ppm	316ppm
Sulphated Ash	NMT 0.1%	0.0007
Heavy Metal	NMT 200ppm	<20ppm
Water	NMT 3.0%	0.018
Assay(on anhydrous and solvent free basis)	≥95%	0.981

Veterinary Drug Doramectin Powder CAS 117704-25-3 99% Doramectin

Function and Application

Doramectin is used for the treatment of ectoparasitic diseases such as nematode diseases and mites of domestic animals. It is produced by the fermentation of a new strain of Streptomyces avermitilis, which is genetically recombined. The main difference from ivermectin is that the C25 position is cyclohexyl. Instead, it is a new, broad-spectrum antiparasitic drug that is highly effective against gastrointestinal nematodes, lung nematodes, euglena, lice, ticks, mites and wound maggots, and against internal and external parasites, especially certain nematodes (roundworms) And arthropods also have a good repellent effect, but it is ineffective against tapeworms, trematodes and protozoa.

Its mechanism of action is mainly to increase the release of the inhibitory transmitter gamma aminobutyric acid (GABA) of the worm, thereby blocking the transmission of nerve signals, making muscle cells lose the ability to contract, and causing the death of the worm. The peripheral neurotransmitter of mammals is acetylcholine, which will not be affected by doramectin. Doramectin does not easily penetrate the blood-brain barrier and has minimal damage to the central nervous system. It is relatively safe for livestock. The main feature is that the blood concentration and half-life are both higher or twice as long as ivermectin.

Veterinary Drug Doramectin Powder CAS 117704-25-3 99% Doramectin
Xi'an Wucine Bio Industries Inc is a national key high-tech enterprise,which mainly specializes
in the R&D,operation and production of pharmaceuticals,and intermediates.Our company is
situated in E&T development zone,xi'an city shaanxi,it is easy of access.Our company has
independent R&D center,raw material synthesis workshop,has advanced quality instruments
and equipmentm,several product patents there are 15 experts in our research team.We insist
in innovation and produce high quality products.