Enramycin has a strong activity against Gram-positive bacteria, especially Clostridium in the intestine. After long-term use, it is not easy to develop drug resistance because it changes the bacterial population in the intestine. Therefore, the use of nutrients in feed is good, which can promote weight gain in pigs and chickens and increase feed conversion rates. Enramycin oral LD50 was 10g per kilogram of weight in large mice and 522.9 mg in 4 weeks of age. However, Enramycin(crude crystal) used for feed addition was oral, 11 g per kg of body weight in rats and mice and 8 g in broilers. Teratogenic and mutagenicity tests were negative. After oral administration, Enramycin only plays a role in the digestive tract and is not easily absorbed. After 6 to 12 H of administration of the chicken, enramycin excreted in the faeces reached 87.0 % to 100 %, and the residue of the piglets was very small. After 1 week of continuous use, the residue in the tissues was less than 25 μg / kg on the same day. Enramycin has no toxic effect on crops, fish and the environment after it is discharged by chickens and pigs. Therefore, it is a safe and effective animal specific antibiotic. Enramycin is preserved at 40 °C for 4 months, and the price is still above 90 %, but the price is reduced when the humidity is high. Enramycin is stored at room temperature for 12 weeks in the added feed, and the potency is not less than 90 %.