China Cosmetic Grade Hydroxypropyl Beta Cyclodextrin, Find details about China Hydroxypropyl Beta Cyclodextrin, 128446-35-5 from Cosmetic Grade Hydroxypropyl Beta Cyclodextrin
Hydroxypropyl beta-cyclodextrin are purified polydisperse products resulting from the controlled reaction of propylene oxide and native beta-cyclodextrin. Hydroxypropyl beta-cyclodextrin is itself very soluble in water (greater than 500 mg/ml at room temperature compared to 18 mg/ml for beta-cyclodextrin), and is used for molecular encapsulation of a variety of sparingly water compounds to enhance the aqueous solubility of the encapsulated compound.
Hydroxypropyl beta-cyclodextrin (HBC) is a widely used modified cyclodextrin, consisting of 7 glucose units forming liposophile cavities. After complexation of the drug with hydroxypropyl - -cyclodextrin, the water solubility will be greatly enhanced. The number of 2-hydroxypropyl groups is between 5 and 14.
Product name | Hydroxypropyl beta-cyclodextrin |
Appearance | White Powder |
CAS | 128446-35-5 |
MF | C63H112O42 |
MW | 1541.54 |
Hydroxypropyl -beta-cyclodextrin is an ideal injection solubilizing agent and drug excipient. It can improve the water-solubility of insoluble drugs, increase the stability of Chemicalbook, improve the bioavailability of drugs, increase the efficacy or decrease the dosage of drugs, adjust or control the release rate of drugs, and reduce the toxic and side effects of drugs.
1. In the field of food and spices, it can improve the stability and long-term effect of nutrition molecules, mask or correct the bad smell and taste of food nutrition molecules, and improve the production process and product quality of Chemicalbook. The product has good solubility in water and can be miscible with water in any proportion with degree of substitution 4 or above. It can also be dissolved in 50% ethanol and methanol.
2. Used as stabilizer, emulsifier and deodorant in cosmetic raw materials, it can reduce the stimulation of organic molecules in cosmetics on skin mucosal tissues, enhance the stability of active ingredients, and prevent the volatilization and oxidation of nutrients. It has some relative hygroscopicity.
3. In the pharmaceutical industry, it is an ideal solubilizer for injection and drug excipient due to its relatively low surface activity and hemolytic activity and no irritation to muscles.