High-Quality Anti-Wrinkle Multi-Peptides Acetyl Hexapeptide-3; CAS No. 616204-22-9; Acetyl Hexapeptide-8; AC-Glu-Glu-Met-Glu-Arg-Arg-Nh2
China High-Quality Anti-Wrinkle Multi-Peptides Acetyl Hexapeptide-3; CAS No. 616204-22-9; Acetyl Hexapeptide-8; AC-Glu-Glu-Met-Glu-Arg-Arg-Nh2, Find details about China CAS No. 616204-22-9, Acetyl Hexapeptide from High-Quality Anti-Wrinkle Multi-Peptides Acetyl Hexapeptide-3; CAS No. 616204-22-9; Acetyl Hexapeptide-8; AC-Glu-Glu-Met-Glu-Arg-Arg-Nh2
Basic Info.
Model NO.
Cosmetic Peptide
Certifications
SGS; ISO; GMP; FDA; cGMP; Cos
Sample
Available
Documents
Moa;MSDS;COA;Ros;Hnmr, Cnmr, Ms
Tp
Available
Trademark
High-quality Products
Transport Package
1g/1kg/5kg Bag/Tin/Carton
Specification
Inhouse; Customer Standards
Origin
China
HS Code
2935900090
Model NO.
Cosmetic Peptide
Certifications
SGS; ISO; GMP; FDA; cGMP; Cos
Sample
Available
Documents
Moa;MSDS;COA;Ros;Hnmr, Cnmr, Ms
Tp
Available
Trademark
High-quality Products
Transport Package
1g/1kg/5kg Bag/Tin/Carton
Specification
Inhouse; Customer Standards
Origin
China
HS Code
2935900090
Product Desciption
Acetyl Hexapeptide-8
CAS No: 616204-22-9
INCI Name: Acetyl Hexapeptide-8
CAS No.: 616204-22-9
Molecular Formula: C34H60N14O12S
Molecular weight: 888.9918
Product introduction:
The earliest and most extensive six peptides, also known as botulinum toxin peptides, can effectively reduce the depth of wrinkles caused by facial muscle contractions, especially wrinkles around the forehead and eyes.
Mechanism of action:
Acetylhexapeptide-8 is the N-terminal analogue of SNAP-25, so it can compete with SNAP-25 to form SNAP-25 protein complex. Normal SNAP-25 binding SNRE triggers the release of acetylcholine between synapses, which makes neurotransmission possible. Acetylhexapeptide-8 binding causes the instability of SNAP complex. Thus affecting the release of neurotransmitters, but also hindered muscle contraction, prevent wrinkles and fine lines.
Benefits:
Reduce wrinkle depth
Prevents the formation of wrinkles and fine lines
Physical and chemical indicators:
Appearance: White Powder
Color: White
PH: 4.5-6.8
Solubility: soluble in water.
Refractive index (20ºC): 1.3357-1.3387
Product specification:
Packing specification: 1 kg/ bottle and 5 kg/ bottle.
Component information: Acetyl Hexapeptide-8, Water, Glycerol, Ethylhexylglycerin, Phenoxyethanol
Content: 500ppm
Microbial count: <100 CFU/ml
Specific pathogens: none
Security
Basic skin irritation test: no signs of irritation or swelling were observed after 7 d of albino male rabbit test.
Acute oral administration toxicity test: There were no toxic symptoms at various doses by intraperitoneal injection and intragastric administration. The experiment was observed for 20 days. The results showed that the biosafety of Botulinum-like peptide samples was good under the condition of acute single contact.
Skin sensitization test: human repeated patch test was performed in 50 volunteers aged 17 to 75.The Botulinum-like peptide does not cause any allergic reaction.
Usage and dosage
Add below 45 ºC, recommended addition 0.5-5%
Storage and shelf life
The transportation process is stored at 25 ºC. If stored for a long time, the original package is sealed and placed at 2-8 ºC for 2 years. In order to avoid secondary pollution, it should be used as soon as possible after opening the cover.
Effect of the test
A female subject was wiped around her eye once in the morning and evening with a blank emulsion and an emulsion containing 5% Botulinum-like peptide, and the silicon imprinting was obtained before and after 30 days of test. Silicon imprinting was analyzed by confocal scanning microscopy to assess changes in the skin surface before and after treatment. The results showed that the depth of wrinkles was significantly reduced after 30 days of treatment with Botulinum-like peptide, which confirmed the physiological hypothesis that Botulinum-like peptide can treat wrinkles.
Applications:
* SK-II elastic anti-relaxation serum
* SK-II Firming Serum
* Estee Lauder Youth Anti-wrinkle Night Cream
* Estee Lauder Elastic Firming Firming Cream
La Mer The Treatment Lotion
CAS No: 616204-22-9
CAS No.: 616204-22-9
Molecular Formula: C34H60N14O12S
Molecular weight: 888.9918
Product introduction:
The earliest and most extensive six peptides, also known as botulinum toxin peptides, can effectively reduce the depth of wrinkles caused by facial muscle contractions, especially wrinkles around the forehead and eyes.
Mechanism of action:
Acetylhexapeptide-8 is the N-terminal analogue of SNAP-25, so it can compete with SNAP-25 to form SNAP-25 protein complex. Normal SNAP-25 binding SNRE triggers the release of acetylcholine between synapses, which makes neurotransmission possible. Acetylhexapeptide-8 binding causes the instability of SNAP complex. Thus affecting the release of neurotransmitters, but also hindered muscle contraction, prevent wrinkles and fine lines.
Benefits:
Reduce wrinkle depth
Prevents the formation of wrinkles and fine lines
Physical and chemical indicators:
Appearance: White Powder
Color: White
PH: 4.5-6.8
Solubility: soluble in water.
Refractive index (20ºC): 1.3357-1.3387
Product specification:
Packing specification: 1 kg/ bottle and 5 kg/ bottle.
Component information: Acetyl Hexapeptide-8, Water, Glycerol, Ethylhexylglycerin, Phenoxyethanol
Content: 500ppm
Microbial count: <100 CFU/ml
Specific pathogens: none
Security
Basic skin irritation test: no signs of irritation or swelling were observed after 7 d of albino male rabbit test.
Acute oral administration toxicity test: There were no toxic symptoms at various doses by intraperitoneal injection and intragastric administration. The experiment was observed for 20 days. The results showed that the biosafety of Botulinum-like peptide samples was good under the condition of acute single contact.
Skin sensitization test: human repeated patch test was performed in 50 volunteers aged 17 to 75.The Botulinum-like peptide does not cause any allergic reaction.
Usage and dosage
Add below 45 ºC, recommended addition 0.5-5%
Storage and shelf life
The transportation process is stored at 25 ºC. If stored for a long time, the original package is sealed and placed at 2-8 ºC for 2 years. In order to avoid secondary pollution, it should be used as soon as possible after opening the cover.
Effect of the test
A female subject was wiped around her eye once in the morning and evening with a blank emulsion and an emulsion containing 5% Botulinum-like peptide, and the silicon imprinting was obtained before and after 30 days of test. Silicon imprinting was analyzed by confocal scanning microscopy to assess changes in the skin surface before and after treatment. The results showed that the depth of wrinkles was significantly reduced after 30 days of treatment with Botulinum-like peptide, which confirmed the physiological hypothesis that Botulinum-like peptide can treat wrinkles.
Applications:
* SK-II elastic anti-relaxation serum
* SK-II Firming Serum
* Estee Lauder Youth Anti-wrinkle Night Cream
* Estee Lauder Elastic Firming Firming Cream
La Mer The Treatment Lotion
Our manufacturer has introduced ISO9001 quality management system certification, realizing the whole process control through product design, raw
material procurement, production process, quanlity assurance, product sales to after service;
Our manufacturer has fully implemented GMP/FDA/CEP management, GMPDA/CEP certifications are available.
Our manufactuer always takes innovation as the core, and attaches great importance to the improvement of its R & D comprehensive strength.
material procurement, production process, quanlity assurance, product sales to after service;
Our manufacturer has fully implemented GMP/FDA/CEP management, GMPDA/CEP certifications are available.
Our manufactuer always takes innovation as the core, and attaches great importance to the improvement of its R & D comprehensive strength.
1. We can offer you sample for testing.
2. We can pack the material as per your requirement.
3. We can provide you TP documents along shipment.
4. We can accept your audit if necessary near future.
5. We can offer the material as per your specification.
6. We can customize the product as per your specification.
7. We can arrange shipment professional and efficient.
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