Description of Mifepristone CAS 84371-65-3

 

Introduction for Mifepristone CAS 84371-65-3

Product name:Mifepristone
English Synonyms: 11-(4-(dimethylamino)phenyl)-17-hydroxy-17-(1-propynyl)-estra-9-dien-3-one;11beta-[4-(n,n-dimethylamino)phenyl]-17alpha-(prop-1-ynyl)-delta4,9-estradiene;17-beta)-(11-bet;17beta)-11-[4-(dimethylamino)-phenyl]-17-hydroxy-17-(1-propynyl)estra-(11bet;17-beta-hydroxy-11-beta-(4-dimethylaminophenyl-1)-17-alpha-(prop-1-ynyl)oest;-17beta-ol-3-one;4,9-dien-3-one;r38486 
CAS NO.: 84371-65-3 
Assay: 98%
Molecular Formula:C29H35NO2 
Molecular Weight:429.59 
Melting point: 150ºC
Appearance: Light yellowish powder
Packing:1kg/tin
Usage: New anti-progesterone, and has anti-glucocorticoid activity, but not progesterone, estrogen, androgen and anti-estrogen activity. And progesterone receptor affinity 5-fold stronger than progesterone. For anti-early pregnancy, reminders by only pregnancy, fetal death, uterine induction of labor, etc.

Mifepristone was the first antiprogestin to be developed and it has been evaluated extensively for its use as an abortifacient. The original target for the research group, however, was the discovery and development of compounds with antiglucocorticoid properties. These antiglucocorticoid properties are of great interest in the treatment of severe mood disorders and psychosis, although a review of published articles was inconclusive on their efficacy, and considered the use of these drugs in mood disorders at 'proof of concept' stage. It is on the World Health Organization's List of Essential Medicines.

Specification of Mifepristone CAS 84371-65-3
 

Applications of  Mifepristone CAS 84371-65-3

Mifepristone (also known as RU 486) is used to cause an abortion during the early part of a pregnancy. It is used up to week 10 of pregnancy (up to 70 days after the first day of your last menstrual period). Mifepristone blocks a natural substance (progesterone) that is needed for your pregnancy to continue.It is usually used together with another medicine called misoprostol. Mifepristone must not be used if you have a rare abnormal pregnancy that is outside the womb (ectopic pregnancy). It will not cause an abortion in this case. Mifepristone may cause an ectopic pregnancy to rupture, resulting in very serious bleeding.

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