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What is J-147?
J147 was discovered based upon efficacy in multiple cell culture models of age-associated pathologies rather than exclusively amyloid metabolism.
It is an exceptionally potent, orally active and broadly neuroprotective compound has the ability to enhance memory in normal animals as well as to prevent memory deficits in Alzheimer's disease (AD) transgenic mice.
The neurotrophic and memory-enhancing activities of J147 are associated with an increase in brain derived neurotrophic factor (BDNF) levels and the expression of BDNF responsive proteins, the enhancement of LTP, the preservation of synaptic protein, the reduction of amyloid plaques, etc.
J-147 Benefits
J-147 is a novel neurotrophic drug for cognitive enhancement and alzheimer's disease. J-147 is an exceptionally potent, orally active and broadly neuroprotective compound has the ability to enhance memory in normal animals as well as to prevent memory deficits in alzheimer's disease (ad) transgenic mice. the neurotrophic and memory-enhancing activities of J-147 are associated with an increase in brain derived neurotrophic factor (bdnf) levels and the expression of bdnf responsive proteins, the enhancement of ltp, the preservation of synaptic protein, the reduction of amyloid plaques.
J-147 Mode of Action
The J147 drug is also reported to address other biological aging factors, such as preventing the leakage of blood from microvessels in mice brains. The development of J147 follows the chemical pharmacological way, contrary to biological ways that exploit e.g. use of bacteriophages.
Enhanced neurogenic activity over J147 in human neural precursor cells has its derivative called CAD-31. CAD-31 is enhancing the use of free fatty acids for energy production by shifting of the metabolic profile of fatty acids toward the production of ketone bodies, a potent source of energy in the brain when glucose levels are low.

 

Application
The target molecule is a protein called ATP synthase, which is found in the mitochondria. 
1.Improved learning and recall abilities, useful in general and particularly for students.
2.Improving Memory.
3.Improving the brain function.
4.Preventing and treating senile dementia.
5.Enhancing the learning ability.
6.Increasing the attention.
7.Relieving the anxiety.
8.Flmodafinil can be helpful in the treatment of minor depression. Some users have reported the restoration of regular mood.

Product Description

Related products(Not limited to that, you name it, we make it.)

Port:Tianjin Port

Why Choose Us?
 
1.Full experience of large numbers containers loading in Chinese sea port.
2.Fast shipment by reputed shipping line.
3.Packing with pallet as buyer's special request.
4.Best service after shipment with e mail.
5.Cargoes together with container sales service available.
6.Full experience for export.
7.Cargoes photo before and after loading into container.
8.Raw materials from Chinese origin.

Q: How to start orders or make payments?
A:You can send our your Purchase order(if your company has), or just send a simple confirmation by email or by Trade Manager, and we will send you Proforma Invoice with our bank details for your confirmation, then you can make payment accordingly.
Q: How to confirm the Product Quality before placing orders?
A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.
Q: What's your MOQ?
A:For the high value product, our MOQ starts from 1g and generally starts from 10gs. For other low price product, our MOQ starts from 100g and 1kg.
Q: Is there a discount?
A: Yes, for larger quantity, we always support with better price.
Q:How do you treat quality complaint?
First of all, our quality control will reduce the quality problem to near zero. If there is a quality problem caused by us, we will send you free goods for replacement or refund your loss.
Q:How to contact us ?
 
You can choose your interested products and send inquiry to us.
You can dial our telephone directly, you will get our reply.