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Product Name | Amphotericin B |
CAS NO | 1397-89-3 |
Molecular Weight | 924.079 |
Density | 1.3±0.1 g/cm3 |
Boiling Point | 1140.4±65.0 °C at 760 mmHg |
Molecular Formula | C47H73NO17 |
Melting Point | >170°C |
Flash Point | 643.5±34.3 °C |
Amphotericin B Picture show:
Tests | Specifications | Results | |
Appearance | Yellow to orange powder, odorless or practically so. | Yellow powder | |
Solubility | Insoluble in water and in ether,slightly soluble in methanol | Complies | |
Identification A: (UV) | Conforms to standard; absorbance in the range of 240nm to 320nm | Complies | |
Identification B: (UV/Vis ) | Conforms to standard; absorbance in the range of 320nm to 400nm | Complies | |
Loss on drying | Not more than 5.0% | 1.5% | |
Residue on Ignition | Not more than 3.0% | 0.4% | |
Limit amphotericin A | Not more than 15.0% | Not detected | |
Assay (microbial) | Not less than 750 μg/mg calculated on the dried basis | 894 μg/mg | |
Residual Solvents | Ethanol | Not more than 5000 ppm | 3309ppm |
Acetone | Not more than 5000 ppm | 1346ppm | |
Conclusion | Complies with USP34 |
Amphotericin B is a pharmaceutical ingredient used for as an antifungal drug often used intravenously for systemic fungal infections.
Amphotericin B is the only effective treatment for some fungal infections.