Bulk API GMP Tamsulosin HCl CAS No: 106463-17-6

China Bulk API GMP Tamsulosin HCl CAS No: 106463-17-6, Find details about China Tamsulosin HCl Powder, Tamsulosin HCl from Bulk API GMP Tamsulosin HCl CAS No: 106463-17-6

Model NO.
Frazer-Tamsulosin HCl
Appearance
White Powder
CAS No
106463-17-6
Shelf Life
2 Years
Test Method
HPLC
Storage
Store Cool Dry Place
Resource
Natural
Quality Requirement
Strictly Quality Control
Product Name
Tamsulosin Hydrochloride
Trademark
Xi′an Frazer Biotech Co., Ltd.
Transport Package
Foil Bag
Specification
99%
Origin
China
Model NO.
Frazer-Tamsulosin HCl
Appearance
White Powder
CAS No
106463-17-6
Shelf Life
2 Years
Test Method
HPLC
Storage
Store Cool Dry Place
Resource
Natural
Quality Requirement
Strictly Quality Control
Product Name
Tamsulosin Hydrochloride
Trademark
Xi′an Frazer Biotech Co., Ltd.
Transport Package
Foil Bag
Specification
99%
Origin
China
Bulk API GMP Tamsulosin HCl CAS No: 106463-17-6Bulk API GMP Tamsulosin HCl CAS No: 106463-17-6
Bulk API GMP Tamsulosin HCl CAS No: 106463-17-6

Items

Specification

Characteristics

White or almost white crystalline powder,

Slightly soluble in water, freely soluble in for mic acid,slightly soluble in anhydrous ethanol.

Melting point

about 230°C

Identification

1) should conformed

2) specific rotation: -17.5° to -20.5°

3) examine by infrared absorption spectrophotometry,compare the spectrum obtained with reference spectrum:should meet the requirements

4) should conformed

Related substances

Method A (EP method):

Largest single impurity should ≤0.1%

Method B(EP method):

Largest single impurity should≤0.1%

Total impurities should ≤0.2%

Enantiomeric purity

≤0.1%

Heavy metals

≤20ppm

Loss on drying

≤0.5%

Sulphated ash

≤0.1%

Assay

98.5% ~ 101.0%


Tamsulosin hydrochloride is the hydrochloride form of Tamsulosin. It is a kind of medication used for the treatment of symptomatic benign prostatic hyperplasia (BPH), boosting the passage of kidney stones. It can also be used for the treatment of acute urinary retention. It is a kind of selective antagonist of alpha-1A and alpha-1B-adrenoceptros located in prostate, prostatic capsule, prostatic urethra, and bladder neck. The blockage of these receptors through Tamsulosin causes the relaxation of smooth muscles in the bladder neck and prostate.

Function of Tamsulosin HCL

Tamsulosin HCL is used for treatment of urination disorders caused by benign prostatic hyperplasia.

Application of Tamsulosin HCL

Adverse reactions
1. the spirit of nervous system: occasionally symptoms such as dizziness, a sense of faltering.
2. the circulatory system: an occasional decrease heart rate, blood pressure, and so on.
3. allergic reactions: occasionally rash, this should stop taking the medication when the symptoms occur.
4. the digestive system: occasionally nausea, vomiting, upset stomach, abdominal pain, loss of appetite, etc.
5. liver: occasionally GOT, GPT, elevated LDH.
6. other: usually reserved for nasal congestion, swelling, difficulty swallowing, tiredness, etc.Bulk API GMP Tamsulosin HCl CAS No: 106463-17-6