China Factory Supply Procaine/Procaine HCl/ Procaine Hydrochloride CAS 51-05-8, Find details about China Procaine Powder, Lidocaine from Factory Supply Procaine/Procaine HCl/ Procaine Hydrochloride CAS 51-05-8
Product name :Procaine hydrochloride
Other name : TIMTEC-BB SBB001081;bernocaine;cetain;chlorocaine;diethylaminoethanol4-aminobenzoatehydrochloride;ethocaine;eugerase;irocaine
CAS register number: 51-05-8
EINECS : 200-077-2
Molecular formula : C13H21ClN2O2
Molecular weight : 272.77
Assay : 99.5%
Appearance : White crystalline powder
Package :1kg/aluminium foil bag or as required
Usage : Can be used as pharmaceutical Local anesthetics
Description:
Procaine hydrochloride is a topical anesthetic, which can block the nerve fiber conduction temporarilyand has a narcotic effect,strong effect, low toxicity, and non-addictive, but on the skin, mucosal penetration is weak, unsuitable for surface anesthesia, patients are used for infiltration, conduction and spinal anesthesia.
White fine needle crystal or crystalline powder at room temperature, no smell, taste slightly bitter and Ma, soluble in water, soluble in ethanol, slightly soluble in chlorofor m, almost insoluble in ether. Procaine hydrochloride ester bond structure can be hydrolyzed to produce amino acid and diethylaminoethanol, under certain conditions, the amino acid may be further decarboxylated toxic anili ne.
The structure of procaine hydrochloride with aromatic primary amino, easy oxidation discoloration pH, temperature, UV, oxygen and metal ions can accelerate the oxidation discoloration. The aqueous solution was stable in pH3.0~5. So preparation of procaine hydrochloride injection, it generally takes add acid to regulate pH 3.3 to 5.5, and strictly control the sterilization temperature and time. to 100 ºC steam sterilization 30min circulation is appropriate, and should pay attention to shading, sealed save.
The product structure of aromatic primary amino group in dilute can generate diazonium salt with sodium n itrite, coupling reaction occurs when add alkaline β-naphthol, generating azo compounds scarlet.
Usage:
Procaine is a local anesthetic of the amino ester group that is primarily used as a topical anesthetic. Procaine is also used to control the pain of intramuscular injection of penicillin as well as in dentistry.
Is there a customs problem with procaine ?
Product name | Procaine |
CAS | 59-46-1 |
M.F | C13H20N2O2 |
M.W. | 236.3101 |
Test Items | Specification | Test Results |
Appearance | White crystals or a white crystalline powder | Conform |
Identification | A\B\E. It appears positive reaction | |
Melting point | 154degree~158degree | 154degree~157degree |
Acidity | PH 5.0~6.5 | PH=5.9 |
Appearance of solution | Clear and colourless | Conform |
Loss on drying | ≤0.5% | 0.07% |
Heavy metals | ≤0.0005% | Conform |
Related substances | ≤0.05% | Conform |
Sulphated ash | ≤0.1% | 0.05% |
Assay ( on dry basis ) | 99.0-101.0% | 99.87% |
Conclusion | Conform to BP2005 |
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