China Chlortetracycline HCl 64-72-2 Chlortetracycline Hydrochloride/Pyrantel Pamoate 22204-24-6/Doxycycline Hydrochloride 10592-13-9/24390-14-5 Doxycycline Hyclate, Find details about China Doxycycline Hyclate, 24390-14-5 from Chlortetracycline HCl 64-72-2 Chlortetracycline Hydrochloride/Pyrantel Pamoate 22204-24-6/Doxycycline Hydrochloride 10592-13-9/24390-14-5 Doxycycline Hyclate
Introduction
Product Information | |
Other Name | Doxycycline Hyclate |
Assay | 99% |
Apprearance | Yellow crystalline powder |
Package | 1kg/carton; 25kg/drum |
Payment | Alipay; Western Union; TT |
Shipment | DHL; FedEx, EMS; Air; Sea |
Standard | USP/EP/CP/BP |
Storage | Sealed in dark and dry place |
Shelf Life | 2 Years |
Doxycycline Hyclate is antibacterial spectrum is very close to Tetracycline and Terramycin, but it has better effect, be sensitive to the Staphylococcus Aureus of tetracycline-resistant, oxytetracycline, long lasting time.It is often used in Senile Chronic Bronchitis, respiratory tract infection, lung infection, acute tonsillitis, mycoplasma pneumonia, urinary tract infection, blood poisoning, bacillary dysentery, acute lymphadenitis, etc. It is very popular to Nephropathy patient because of its unobvious poisoning for kidney.
Application
1. Almost the same Antibacterial spectrum with tetracycline and oxytetracycline,
Doxycycline Hyclate has the stronger inside and outside antibacterial effect than tetracycline.
2. Microorganism has closely cross-resistance with Doxycycline Hyclate, and tetracycline and oxytetracycline. Good oral absorption.
3. Mainly used on upper respiratory tract infection, tonsillitis, biliary tract infection, lymphadenitis, honeycomb group inflammation, chronic bronchitis caused by sensive Gram-
4. positive bacteria and gram-negative bacilli.
It can be also used to control Typhus, Qiang echinococcosis, mycoplasma pneumonia.
And used to control cholera, and prevent Falciparum malaria and leptospirosis infection
Specification
Items | Specifications | Results |
Appearance | Yellow crystalline powder | Conforms |
Identification | TLC | Conforms |
sulphuric acid reaction a yellow colour develops | Conforms | |
it gives reaction of chlorides | Conforms | |
PH | 2.0~3.0 | 2.3 |
Specific absorbance | at 349nm e(1%) 300~355 | 320 |
Specific optical rotation | -105 ~ -120° | -110° |
Heavy metals: | ≤50ppm | < 20ppm |
Light-absorbing impurities | at 490nm ≤0.07 | 0.03 |
Related substances | 6-epidoxycycline ≤2.0% metacycline ≤2.0% 4-epidoxycycline ≤0.5% (ep5) 4-epi-6-epidoxycycline ≤0.5% (ep5) oxytetracycline ≤0.5% (ep5) any other impurity ≤0.5% not identified impurities ≤0.1% (ep5) | 1.6% 0.1% Not found Not found Not found Not found Not found |
Ethanol | 4.3~6.0% (m/m) | 4.5% |
Sulphated ash | ≤0.4% | 0.05% |
Water | 1.4~2.8% | 1.8% |
Assay | 95.0~102.0% ( c22h25cln2o8) based on anhydrous, ethanol-free substance | 98.6% |
Conclusion | Conform with USP32 |