China Faithful Supply Sulbutiamine/Bisibutiamine 3286-46-2//Tocotrienol 490-23-3//24390-14-5 Doxycycline Hyclate//10592-13-9 Doxycycline Hydrochloride, Find details about China Doxycycline Hydrochloride, 10592-13-9 from Faithful Supply Sulbutiamine/Bisibutiamine 3286-46-2//Tocotrienol 490-23-3//24390-14-5 Doxycycline Hyclate//10592-13-9 Doxycycline Hydrochloride
Introduction
Name | Doxycycline hydrochloride |
CAS | 10592-13-9 |
MF | C22H25ClN2O8 |
Purity | 99% |
Color | Yellow |
Appearance | powder |
MOQ | 1kg |
Origin | China |
MW | 285.92 |
Doxycycline is antibiotic medicine, tetracycline drugs, treatment for chlamydia mycoplasma infection. Its character is yellow or pale yellow crystalline powder, odor, taste bitter. Easily dissolved in water and methano,slightly soluble in ethanol or aceton, insoluble in chlorofom.
Function
1. Treat a wide variety of bacterial infections and stop the growth of bacteria.
2. Prevent malaria
Mainly used for the treatment of respiratory tract, urinary tract caused by sensitive bacteria and biliary tract infection. Antibacterial spectrum and tetracycline, oxytetracycline basic same, the body, antibacterial outside force is stronger than tetracycline. This product is closely related to tetracycline and oxytetracycline microbial cross resistance. Oral absorption is good. Mainly used for sensitive gram-positive bacteria and gram-negative bacteria caused by upper respiratory tract infection, tonsillitis, biliary infection, lymphadenitis, cellulitis, geriatric chronic bronchitis, etc., also used in the treatment of typhus, qiang worm disease, such as mycoplasma pneumonia. Can be used in the treatment of cholera, can also be used to prevent malignant malaria and leptospira infection.Resistant to doxycycline, doxycycline and minocycline to semisynthetic tetracycline drugs, antibacterial effect than natural.Doxycycline is stronger, the usage is wider, resistance is small, belongs to the animal toxicity to the horse, pig, chicken and big dosage of small animals.
Application
Almost the same Antibacterial spectrum with tetracycline and oxytetracycline, Doxycycline Hyclate has the stronger inside and outside antibacterial effect than tetracycline.Microorganism has closely cross-resistance with Doxycycline Hyclate, and tetracycline and oxytetracycline.Good oral absorption.
Mainly used on upper respiratory tract infection, tonsillitis, biliary tract infection, lymphadenitis, honeycomb group inflammation, chronic bronchitis caused by sensive Gram-positive bacteria and gram-negative bacilli.It can be also used to control Typhus, Qiang echinococcosis, mycoplasma pneumonia.And used to control cholera, and prevent Falciparum malaria and leptospirosis infection.
Specification
Items | Specifications | Results |
Appearance | Yellow crystalline powder | Complies |
Identification | TLC | Complies |
sulphuric aci reaction a yellow colour develops | Complies | |
it gives reaction of chlorides | Complies | |
PH | 2.0~3.0 | 2.7 |
Specific absorbanc | at 349nm e(1%) 300~355 | 320 |
Specific optical rotation | -105 ~ -120° | -110° |
Heavy metals: | ≤50ppm | < 50ppm |
Light-absorbing impurities | at 490nm ≤0.07 | 0.045 |
Related substances | 6-epidoxycycline ≤2.0% | 1.46% |
metacycline ≤2.0% | 0.10% | |
4-epidoxycycline ≤0.5% (ep5) | Not found | |
4-epi-6-epidoxycycline ≤0.5% (ep5) | Not found | |
oxytetracycline ≤0.5% (ep5) | Not found | |
any other impurity ≤0.5% | Not found | |
not identified impurities ≤0.1% (ep5) | Not found | |
Ethanol | 4.3~6.0% (m/m) | 4.37% |
Sulphated ash | ≤0.4% | 0.05% |
Water | 1.4~2.8% | 1.80% |
Assay | 95.0~102.0% ( c22h25cln2o8) | 97.98% |
Based on anhydrous, ethanol-free substance | ||
Conclusion | This product comforms with USP39 |