Ly 294002 Hydrochloride 154447-36-6 Pi3K Inhibitor

China Ly 294002 Hydrochloride 154447-36-6 Pi3K Inhibitor, Find details about China Ly294002, 154447-36-6 from Ly 294002 Hydrochloride 154447-36-6 Pi3K Inhibitor

Model NO.
154447-36-6
Appearance
Powder
Storage Conditions
2-5 Sealed, Protected From Light and Moisture
Trademark
Chenxun
Transport Package
Negotiable
Specification
Bottle
Origin
China
HS Code
3808940090
Model NO.
154447-36-6
Appearance
Powder
Storage Conditions
2-5 Sealed, Protected From Light and Moisture
Trademark
Chenxun
Transport Package
Negotiable
Specification
Bottle
Origin
China
HS Code
3808940090
LY 294002 HYDROCHLORIDE 154447-36-6 PI3K Inhibitor

Description

Chemical NameLY294002
SynonymsLY 294002 HYDROCHLORIDE;2-Morpholino-8-phenyl-4-oxo-4H-1-benzopyran;2-Morpholino-8-phenylchromone;2-Morpholino-8-phenyl-4H-chromen-4-one;
CAS No.154447-36-6
Molecular FormulaC19H17NO3
Molecular Weight307.34300
PSA42.68000
LogP3.36160

Properties

Appearance & Physical StatePale yellow solid
Density1.266 g/cm3
Boiling Point494.6ºC at 760 mmHg
Melting Point182-184ºC
Flash Point253ºC
Vapor Pressure6.33E-10mmHg at 25°C

Description
LY294002 is a morpholine-containing chemical compound that is a potent inhibitor of numerous proteins, and a strong inhibitor of phosphoinositide 3-kinases (PI3Ks). It is generally considered a non-selective research tool, and should not be used for experiments aiming to target PI3K uniquely.
Two of these are the proto-oncogene serine/threonine-protein kinase (PIM1) and the phosphatidylinositol-4,5-bisphosphate 3-kinase P110 gamma|catalytic subunit gamma isoform. With an IC50 of 1.4 µM it is somewhat less potent than wortmannin, another well-known PI3 kinase inhibitor. However, LY294002 is a reversible inhibitor of PI3K whereas wortmannin acts irreversibly. Application of LY294002 causes a substantial acceleration of MEPP frequency (150 μM) at the frog neuromuscular junction through a mechanism that is independent of intraterminal calcium. LY294002 causes the release of MEPPs through a perturbation of synaptotagmin function.
LY294002 is also a BET inhibitor

Ly 294002 Hydrochloride 154447-36-6 Pi3K Inhibitor


Ly 294002 Hydrochloride 154447-36-6 Pi3K Inhibitor

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 By Express
Sultable for under 50kg, Fast:3-4 days. High cost; Door to door service. Easy to plck up the goods.
 By Air
Sultable for more than 50 kg, Fast: 4-5 days, HIgh cost, alrport to alrportprofesslonal broker needed.
 By sea
Sultable for more than 500kg. Slow: 15-45 days, Low cost. Port to Port, protesslonal broker needed.


FAQ

Q1: Can i get small sample?
A: Yes, FREE SAMPLES of some products can be sent on request, but the shipping cost be paid by our customers.
Q2. How to confirm the products quality before placing orders?
A: COA first for you to check the specification,and we test every batch of our product
by HPLC.UV,GC AND TLC AND etc. We also cooperate with independent third party
lab such as SGS,PONY etc.  

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